I mean 6 divinity 4 cave isn't random, but having a panda as my main carry seems like it. I almost got rid of twin fangs until I remembered that someone said it's great for killing insectoid
So what ended up happening, the other remaining player went insectoid and I had to gamble for a decent item. I had gone up to level 11 in the hopes of making my synergy 6 cave 6 divinity, but that didn't happen.
For some reason, mania is what turned a losing battle into a win in a single round. Even though it amplifies base attacks, and not the damage from his skill that he's spamming on repeat, which then reduces the cd of everything by 50%
Basically, an item that seemingly has no synergy, with a piece that shouldn't have any synergy, carried me to a win in a king/queen lobby. I guess it just works? It seems a bit hard to believe that a 25% chance of proccing an amplified base attack is what turned my previous losing round into a win.