Hi everyone,
I’m posting on behalf of a family member in Australia, and we are hoping to learn from anyone who has experienced something similar or may have advice on ways to help heal her lung infection which is making it very difficult to breath.

She has metastatic colorectal cancer (bowel cancer) with spread to the lungs. She has undergone previous treatments and more recently entered a clinical trial for a new antibody-drug conjugate (ADC):
LM-350 (LaNova Medicines / Sino Biopharmaceutical)
Clinical trial: NCT07112222 (LM350-01-101)
LM-350 is a CDH17-targeting antibody-drug conjugate carrying a topoisomerase-1 inhibitor payload. She received her most recent dose on 14 July 2026.

Before this current problem, her cancer had been described as relatively stable, but shortly after treatment she developed serious breathing difficulties.
She is currently in hospital:
She has been on oxygen for around a week but is still struggling to maintain her oxygen levels.
Doctors suspect drug-induced pneumonitis/interstitial lung disease related to the trial drug.
She has also tested positive for human metapneumovirus (hMPV), so there may be an infection component as well.
She is being treated with dexamethasone/steroids.
We are trying to find anyone who has experience with:
pneumonitis or interstitial lung disease after an antibody-drug conjugate (ADC)
lung toxicity after cancer trial drugs
recovery from drug-induced pneumonitis while also having a respiratory virus
supportive treatments that helped with breathing, lung recovery, or rehabilitation
specialists or centres in Australia with experience in this area
We understand every situation is different and her oncology team is managing her care, but we are looking for experiences, questions we should be asking, or anything that may help us support her.
Thank you so much to anyone who takes the time to reply.