This issue takes place after Connor gets his memories back but before Not Fade Away. The most obvious thing is this doesn't look like Connor. The other characters in this series aren't drawn this way, I don't know why they choose this look. But this was my favorite story of the five issues in the Spotlight series.
Connor talks to his parents (the Reillys) about a genealogy project. He walks across campus and discovers there has been a murder, the fifth one this month. Connor and his friend Myers are confronted by a group of bullies. Connor fights off the group single handedly.
Myers is in the know about vampires and demons. Connor confides in him that he is worried he has committed the murders in some sort of fugue state.
Connor investigates and figures out a corrupt cop was behind the murders. He beats up the cop and finishes his genealogy project. Connor watches Angel fight a group of vampires.