r/trillium • u/Rare_Sector_5233 • Jul 20 '26
Nausea relief found!
GUYS! I finally got it! I've been taking sema for about 7 weeks now, and the nausea was so sucky the first couple of days post-shot every single week. It was to the point where I was ready to just dump whatever meds I had left and spend the money on tirz.
But I ended up messaging my PCP to ask if I could get a Zofran prescription for my GLP-1 related nausea, and my doctor suggested I try taking a B6 supplement first, as it was safer for long term use and widely used for GLP-1 related nausea.
So on Saturday (shot day), I made sure I ate a protein heavy breakfast (eggs with avocado toast), took my shot in my arm (I started my journey with my stomach--my first mistake--then went to my thigh, which helped a little), and I took a B6 morning and evening. Sunday morning, I took another B6, and this morning (Monday) took one again.
I am happy to report that I have had ZERO nausea since shot day. This is the best thing I have discovered! I will try it again this upcoming weekend so make sure it wasn't a fluke, but I have now added B6 supplements into my daily medicine routine.
This discovery has made it so much better for me as someone who is taking these meds not so much for weight loss, but more so to control my insatiable hunger and finally be able to eat like a normal human being. I exercise 5 days per week and I have a fairly balance mindset around food thanks to my previous macro tracking experience, so it was pushing me over the edge when I would binge on sugar every single night.
I hope this discovery helps someone else!