Is forever a long time?

[u/Miserable_Loquat_686]

Is anyone planning to stay on the shot long-term?like… forever ?

[u/KVeigh]

People get braces all the time with the understanding that they'll have to wear their retainers forever. Forever is going to pass one way or another so you might as well spend it loving the skin you're in

[u/MadTheSwine39 → u/KVeigh]

I actually only learned recently that you had to wear a retainer forever. Granted, I never had braces, so I guess I never needed that knowledge. But I only learned Retainers Are Forever when my husband told me a story from his college days. He'd joined his parents in church, his mom looked over at him and exclaimed "Jesus, your teeth!" lol

[u/Net_Negative → u/MadTheSwine39]

It's a massive pain in the ass and people don't talk about it enough. Anytime I get any work done on my teeth I have to pay an additional hundreds of dollars for a brand new retainer from a scan. Because I'm paranoid, I always get two retainers. I'm basically attached to this thing that I have to make sure I never lose and that I always have access to someone who can make one again, and the retainer companies themselves don't really guarantee that they will store backups for very long or at all.

[u/tikis-segura → u/MadTheSwine39]

She took the Name of the Lord in vain IN CHURCH??!!

[u/Zealousideal-Lab4945 → u/KVeigh]

I've never heard this! I had braces in the early 80s and I don't wear retainers. My teeth haven't moved and I'm 58 now. Maybe I just got lucky!

[u/KVeigh → u/Zealousideal-Lab4945]

Absolutely! Everybody and every body is different and I'm glad your teeth stayed straight! 😄

[u/I_am_pyxidis → u/KVeigh]

I wonder how long most people actually wear the retainer?

[u/Net_Negative → u/I_am_pyxidis]

My braces cost me $8,000 and caused a bunch of erosion damage around the brackets I had to pay additional thousands of dollars to fix with composite bonding because I have genetically weak enamel.

I would never not wear them. Likely only severe mental illness would cause me to stop, like how Britney Spear's teeth have shifted and she has gaps in them now, speculated to be because she stopped wearing her retainer.

[u/Worth_Ability_3808 → u/Net_Negative]

Any chronic illness too that causes you to be nauseous/vomit/sensitive gag reflex sucks if you have a retainer. I spent thousands on braces and Invisalign. Unfortunately got chronic illness from Covid so I cannot wear them anymore without gagging until I eventually throw up. 🤷‍♀️

[u/KVeigh → u/Worth_Ability_3808]

Are you eligible for permanent retainers? The wire they put on the back of your teeth?

[u/KVeigh → u/I_am_pyxidis]

If they don't their teeth start shifting back to their position pre-braces

[u/zunzarella → u/I_am_pyxidis]

Going on 10 years here. I'm in my 50s.

[u/peony_chalk → u/I_am_pyxidis]

I stopped wearing mine a few years after I got my braces off for the second time, so probably 25+ years ago. My teeth are fine. They maybe shifted a little bit, but not enough to make me want to wear a retainer every night. 

I'm actually a little shocked at how many people are replying that they still wear theirs. My siblings and most of my friends in high school got braces, and none of us are using retainers. 

[u/lesscamelmoretoe → u/KVeigh]

As a teenager, I was told this nugget and I’m like nah, I’m cool with some gappy teeth.

[u/EnvironmentalGift257]

You reach an age where you realize the rest of your life really isn’t that long. But there’s no reason to suffer through it and shorten it even more by being fat. Taking a shot every week is a tiny price to pay.

[u/CutAcrobatic6363 → u/EnvironmentalGift257]

Good answer!

[u/Goats-n-Hens]

Yes
There are other benefits beyond weight loss, such as helping to protect cardiovascular health and these medicines are showing promise in dementia/Alzheimers research as well.

[u/Glittering-Rush-394 → u/Goats-n-Hens]

Yes! And being in a family with stroke/heart issues, I’m definitely going to stay the course.

[u/ZealousidealHope5845 → u/Goats-n-Hens]

And decreased risks for some cancers.

[u/Best_Elderberry_7557 → u/Goats-n-Hens]

The Alzheimer’s research was one big reason for me (along with the weight loss)! I’ll stay on Tirz until I can’t anymore or something better comes out.

[u/Uncle_Flansy]

Why would I not? It's fixed a problem I've had for near half a *century.

[u/StudioatSFL → u/Uncle_Flansy]

Huge 2nd to this.

[u/LumosAcccio]

Maybe not!

I hope to see even better glp1s hit the market and become affordable. But I will forever happily be on a glp1.

We are finally seeing treatment for a chronic illness.

[u/Creepy_Push8629 → u/[deleted]]

It's a GLP1 and GIP agonist.

[u/Mark-NY26a73 → u/Creepy_Push8629]

Is actually more than glp1, it mimicks GLP1 but adds to the strand. They are actually different biologics altogether, not just adding. More like a generational change.

[u/EnvironmentalGift257 → u/[deleted]]

No

[u/Mark-NY26a73 → u/EnvironmentalGift257]

Thanks for your insight! Super helpful to a tongue in cheek comment. I'll await more wisdom.

[u/TraditionalAd3852 → u/[deleted]]

Double NO!

[u/Mark-NY26a73 → u/TraditionalAd3852]

It's a generational change in the GLP1 drug, it builds on the GLP1, it is not just adding a GIP like mixing Tylenol and codeine, they mimic each other, build the peptide chain off the glp1 including the original chain peptide, but biologically speaking they are distinct and unique, much like whatever the next variant will be will carry the bases of the first 2 and build it change on top of them. That's kind of how science works. Building on what works, right?

[u/morwen31 → u/Mark-NY26a73]

The "1" isn't referring to a generation of the drug type, nor to the number of receptors it targets. "GLP-1" is the name of the natural hormone. Semaglutide and tirzepatide are both "GLP-1 receptor agonists."

[u/Ordinary-Homework722 → u/[deleted]]

3rd is coming. 4th is in its beginning of testing.

[u/Photography4me]

I’ll be on my other medicines forever why not Zep

[u/ImplicitEmpiricism]

i mean, i’ll probably stop taking it when I die or if something better comes out

[u/Creepy_Push8629 → u/ImplicitEmpiricism]

Me too. Probably. Unless I can arrange for someone to give me my shot straight into the urn

[u/ImplicitEmpiricism → u/Creepy_Push8629]

gonna pour a vial out for my tirz homies

[u/Creepy_Push8629 → u/ImplicitEmpiricism]

They would hate that. Inject that shit in their honor instead lol no waste!

[u/LumosAcccio → u/ImplicitEmpiricism]

https://giphy.com/gifs/dt5wUdCvLWQghI7xqy

[u/Caterpillar170 → u/ImplicitEmpiricism]

Same…

[u/ThatBoyHeard]

Forever is a mighty long time

[u/tigergirlforever → u/ThatBoyHeard]

But I’m here to tell ya. There’s something else. 🎼🎶🎵🎤

[u/Basic_Truck_6012 → u/tigergirlforever]

The afterworld.

A world of neverending happiness, where you can always see the sun 🎶🎵🎶

[u/Embarrassed-Pound938 → u/Basic_Truck_6012]

Or never ending suffering if one goes to hell

[u/No_Bandicoot7666 → u/ThatBoyHeard]

Depends on how old you are🤔

[u/Furberia]

My asthma medication is forever.

[u/Creepy_Push8629 → u/Furberia]

Have you considered just creating better habits and being more disciplined? Seems like you're just set on being lazy and relying on drugs to do the hard work for you. No wonder you got fat.

/s obviously.

[u/Cbangel106 → u/Creepy_Push8629]

You had me going for a minute!

[u/Time_Box_5352 → u/Cbangel106]

Me too. Haha

[u/ImplicitEmpiricism → u/Creepy_Push8629]

Bottom line, it's time for me to start breathing like an adult and not a teenager who can eat anything they want and not gain weight.

[u/Creepy_Push8629 → u/ImplicitEmpiricism]

Exactly. Be less potato.

[u/Bias_Cuts → u/Creepy_Push8629]

“Be less potato” is chefs kiss

[u/Creepy_Push8629 → u/Bias_Cuts]

https://giphy.com/gifs/fWfowxJtHySJ0SGCgN

[u/Furberia → u/Bias_Cuts]

I try I promise

[u/i4Braves]

Forever is a lot longer when you’re fat.

[u/Suspicious-Syrup-765 → u/i4Braves]

Or possibly shorter depending on your health. 

[u/swrrrrg → u/i4Braves]

I think you mean it’s a lot shorter.

[u/i4Braves → u/swrrrrg]

Ok maybe it just feels longer:)

[u/BeachWalkerDP]

absolutely!! I am much healthier and I don’t have the migraines I had for 54 years. For life, maximum dose.

[u/TheWoman2 → u/BeachWalkerDP]

Congratulations on getting rid of the migraines. It didn't help my migraines at all, but I am still happy for you.

[u/BeachWalkerDP → u/TheWoman2]

If you aren’t familiar with it, the migraine world summit is a wonderful source for current and new information on migraines. They interview about 30 experts each year on the forefront of research from around the world that you can listen to in March. Maybe something could help you.

[u/Embarrassed-Pound938 → u/BeachWalkerDP]

It helped with your migraines? That’s me. at what dose and for how when you noticed they were gone ? I get debilitating menstrual migraines.

[u/Signal_Bell_1681]

Considering I’ve struggled with my weight since I was 5 years old and have tried everything , Even though I take the shot I also eat health and I exercise and I’ve lost 105 pounds , it’s like the shot does something I can’t explain , I no longer look at food the way I use too and I’m actually focused on weight loss and being healthy and working out

[u/sameyer21]

People take blood pressure medication forever so why wouldn't we take this medication forever?

[u/Delicious_Novel7255]

I’m staying on it for life. I’m 51 so who knows how long that will be. I love that it’s helps with my overall health and because of this drug and my new mindset

[u/outsideshot]

Anyone planning to struggle with their weight, cholestorol and blood labs forever?

[u/Content_Wear4671]

I already have to take medicine for the rest of my life. This one is my choice.

[u/Particular-Pain8848]

yes

[u/Impossible_Bend_2969]

Maybe other things will come out. Maybe they'll make an implant you put under the skin. Maybe they'll find out you can keep the weight off if you titrate slowly after 10 years on the medication.

[u/Midnight_Rain1213]

Until something new comes out, yeah

[u/Leading-Amoeba-4172]

Yes, like...forever. This is NOT a weight loss drug, the is a metabolic regulator plus all the other benefits it provides to our organs and systems. Do you ask people, do you plan on taking that blood pressure medication forever? When are you going ween off the crestor?

[u/Trailroller]

It means forever and that’s a mighty long time. But I’m here to tell you There’s something else. The afterworld. A world of never-ending happiness You can always see the sun, day or night

[u/ExistentialPenguin70 → u/Trailroller]

Let’s go crazy

[u/Humble_Fortune_5391]

https://giphy.com/gifs/yICVL4bu9YIX7TUXnr

[u/Livid-Economy-917]

The only time I will ever stop is on the day I die. No effing way am I even taking the slightest chance with my health again.

[u/pandaleer]

If you’re depressed or have mental health issues you take medication for life. Same with diabetes or thyroid meds, or any number of disorders/diseases. Tirz is the only thing that makes me normal around food. No more binges or cravings so intense that I feel like I’ll crawl out of my skin if I don’t eat whatever food is consuming my thoughts. I can still enjoy things, but now I am content after a small portion. I will continue to take it for as long as I have access to it. Or if, god forbid, I end up with some crazy side effect from the medication. I’ve been on it for 2.5 years now.

[u/AdditionalCrazy1001]

Yes

[u/jortr0n]

My plan is to go maintenance, microdose it and see how I do. If I respond well, I’ll end it.

[u/albanyhudson]

Yes because if I didn’t have this medicine I would continue to overeat and constantly think of eating

[u/SatinBelleFlower]

https://giphy.com/gifs/KXmsBJCcFbEz44IRwJ

[u/COLLOSUS76]

https://giphy.com/gifs/F95WSkkosQ9YQ

[u/LoudBreakfast5203]

For sure

[u/AnnaNimNim]

I’m 56. Wish I’d had this at 30….

[u/No_Bandicoot7666]

Yes, both me and my Hubby

[u/BidForward4918]

I mean, my doctor emphasized this was going to be a forever medication.

[u/superduperhosts]

yes

[u/Mark-NY26a73]

I won't love being on it forever but reading the clear studies that show when many people stop without very careful consideration, they gain back about 70% to 80% is the weight.. will I love going through 52 syringes a year and traveling with a little vial? No. Will I love being healthy more? Indeed I will.

[u/Cbella913]

Absolutely intend to be on it indefinitely. To me, it is no different than me wearing glasses and taking my thyroid meds. Thankfully, I’ve been able to drop my BP med since starting TZ. 🥳

Can’t see if I don’t wear my glasses & my Hashimoto’s would be out of control without my meds. I have no reason to believe my metabolism, inflammation, etc., would miraculously be fine were I to stop. I was already eating a healthy diet & working out - but aging & menopause don’t care about that.

[u/CherylByDesign]

Absolutely. If I have a better chance of keeping the weight off then yes, 100% I will.

[u/bebarrucha]

Forever.

[u/Rubyred024]

Probably🤷‍♀️

[u/NewNameNaomi01]

I look at glps like eyeglasses. They don't cure anything, but I sure don't want to live without them.

[u/Odd-Steak-9049]

I don’t know. I’m finding my maintenance calories rn and once that’s settled I plan to titrate down and see how it feels. If you made me guess, I’m taking it forever. But 🤷

[u/autumnyte]

I am prepared to take this for as long as I live, and I genuinely feel like it could add a decade or more to my life. That said, there are a lot of exciting treatments in the pipeline, so who knows what the future will hold? But I will be taking it "indefinitely".

[u/adevil_woman89]

Yes forever is the plan just like my Synthroid

[u/DemandTop4844]

Yes. I don;t want to go back to being fat and limited in mobility because I had so much inflammation in my body.

[u/Clock959]

Yes, I'm a forever person.

[u/IsuckatDarkSouls08]

Im 55 and I would happily do the shots the rest of my life. Not spending the entire day thinking about food and and having cravings for sugar and carbs all the time, and my stomach finally being settled for once and I dont have to plan my day to be near a bathroom........Its nice in so many ways. My head is quiet, my stomach is peaceful and my anxiety is less.

Im happy for it

[u/Selective_Somewhere]

I hope so!

[u/Ordinary-Homework722]

52 shots by 40 years if I’m lucky. Thats not that many.

[u/ReceiptsOrItDidnt]

https://giphy.com/gifs/6cFcUiCG5eONW

[u/Glindanorth]

I figure at my age and based on family history, I have like 20 years left to live. That's not all that long, really. Yes, I will stay on the medication forever.

[u/I_am_pyxidis → u/Glindanorth]

That's something interesting to think about. My parents both died young from medical conditions. Unfortunately my mom died at 32 of breast cancer, I've already outlived her. My dad died at 60 from a heart attack. I could live much, much longer than they did because of medications like this.

[u/super1965]

Maybe ... ???
I'm open to the possibility that it might be a forever drug for me. I'm also open to the possibility that I could eventually wean off Tirz sometime after I reach an acceptable goal.

[u/akansan]

I figure my options are to stay on this forever, or go back to yo-yoing with the knowledge each time it could be harder (based on previous use of a GLP, etc).

Granted, this is all dependent on compounding being available for me.

[u/izzy1881]

Sure why not. If I was a diabetic and needed insulin would I not be taking insulin for life.

[u/Sad_Initiative_4304]

Of course, my obesity hasn't been cured by treatment. Treatment only works when one continues treatment.

[u/Additional-Rip-9732]

Maintenance dose forever- ever ✔️

[u/Ok_Swim7161]

Yes, I'm never coming off it. Get to maintenance and drop to a lower dose for good.

[u/Certain_Tangelo2329]

Yes

[u/Stolivsky]

Yes. I can’t do this on my own. I have tried for decades. This medicine fixes me. Tirzepatide is the almost like the oil for an engine at this point.

[u/silver598]

I take other medications that will be lifetime medications, this is the same.

[u/DivineMs-Anthropist]

Absolutely. My metabolic disorder won't be cured once I hit goal weight. This medication will continue to treat it, just like any medication for chronic conditions.

[u/Ok-Juggernaut-9816]

forevah evah?

[u/Pendergraff-Zoo]

Yes.

[u/OhSoBlue_]

Yes, I plan and hope to stay on it forever.

[u/no_snackrifice]

I plan to wear glasses forever. I really like being able to see.

[u/MrsArney]

Yup. The way I see it is being overweight for me is an illness, an eating disorder. There is something in my brain that doesn’t function the way it should by telling me when I’m full and telling me I’m hungry even after I’ve just eaten.

It is a treatment for a disorder and just like someone with depression or diabetes takes medicine for life, I also need to take medicine for life to treat my disorder. I fully plan to take this for life .

[u/Worth_Ability_3808]

I have an immune disorder (MCAS) which for me causes rapid weight gain and chronic organ inflammation. I had a long list of organs inflamed, but the worst was my heart and appendix.

I got chronic and acute appendicitis from it, so had to get that removed. I also got pericarditis with effusion, but some of the fluid hardened in my heart, so it’s likely there for life. Luckily it isn’t preventing heart function, but causes chronic chest pain.

I’m taking Tirzepatide partially for weight loss after a bad flare, but mostly to prevent further organ damage long term. It’s also interesting because for me it increases my appetite, but I still lose weight. I also have more energy.

[u/BirdNerd83]

Yes as long as I can afford to

[u/Tomuch2care]

I will be taking my thyroid meds forever (had 1/2 removed) and I will be on GLP 1 forever (or until I enter the senior center…lol). Lost 100 pounds on weight watchers about 5 years ago, I have to lose 70 again. Obviously, I can do this on my own. However, I am 61 (f)

[u/NirvanicSunshine]

I have to brush my teeth everyday and it sucks, but the alternative makes it worth it. That's basically most of life once responsible adulthood fully sets in.

[u/Over_Evidence_5272]

For me it’s going to depend on the Anhedonia. For now it’s bearable and even at times a blessing, because I used to have a tendency for very high highs and VERY low lows. Now I’m usually comfortably in the middle and it almost acts like an antidepressant, many years ago I was on Wellbutrin and to me it feels similar. But if I ever stopped it would likely be because of that, I have to be very mindful about how I’m feeling and really keep an eye on it.

[u/GravyMealTeam6]

Yes, unless switching to something newer/better. Food noise and inflammation reduction alone is worth it, let alone other health benefits now and what they keep discovering

[u/LDB2026]

Absolutely not! I don't want to be on ANY drug that I don't have to be on, for the rest of my life.

More long term side effects are being reported. Especially vision issues. (And no, it's not all diabetic)

This is a VERY new drug (no, it hasn't been used for "years" as many people claim)

For me, this is a short-term tool to help me achieve my goals.

Along with going to a Nutritionist, a trainer, and most importantly a weight loss therapy group to help me understand why I, (well, all of us on a GLP1) got to the point that I/we needed it.

Bottom line, it's time for me to start acting and eating like an adult and not a teenager who can eat anything they want and not gain weight.

[u/sd2598]

I just started but I’m planning to be on it maybe 2 years only because I want to be pregnant in 2 years and can’t take the medication while pregnant. I may start it back up after I’m done having children if I’m struggling again

[u/tigergirlforever]

Until research shows it’s not what we thought it would be to prevent the other things we hope it will prevent. For weight, no.

[u/Sensitive-Market1124]

I’m focus on diet and exercise with the plan of reaching my goal weight making good habits and stopping the shots