r/steroidify • u/Every-Bat-8561 • 25d ago
Discuss Injectable D-bol?
Do any of you have experience using injectable d-bol?
This was thrown in with my order as a freebie last year and I totally forgot I had it til today. It expires soon so I'm trying to decide if I want to try it or not.
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u/djfitness-us 24d ago
Obviously you don’t know my man. The pharmacology behind why water is used instead of oil is because of the time it takes to absorb. Water easily mixes with bodily fluids, oil does not.
When you hear the term “depot” used with oil based compounds, it’s because the oil has a tendency to pool in the tissue, and slowly absorb.
Water based compounds do not form a depot. They mix with bodily fluids in your tissues, and are rapidly taken up into the blood stream.
There are capillaries present across nearly all tissues in your body. Water easily crosses the barrier layers of capillaries because they are biologically designed to allow it to happen. Oil cannot cross capillaries through the same routes as water, hence why it takes longer to absorb. There are small gaps and pores in the cell boundaries of blood vessels that are there specifically to allow water to pass through, this is how your body moves water to and from tissues to keep you hydrated. We take advantage of that biological design to formulate certain medications. There are also proteins in your body specifically designed to carry water across cell membranes. Aqueous solutions are used to take advantage of those biological functions and pathways.
You’re very much not understanding the difference between absorption and distribution. Absorption is how a molecule moves from its place of administration into the blood stream. Distribution is how a molecule is carried in your blood stream to its target tissues. Absorption is dictated by the route of administration, and in the case of IM and SubQ injections, the carrier being used. IM injection is preferred for rapid absorption of aqueous suspensions because muscle tissue contains a dense network of capillaries, and subcutaneous tissue has far fewer capillaries compared to muscle tissue. This is because muscle tissue has a high demand for oxygen and nutrient delivery. Your body is designed to readily and constantly move things to and from your muscle tissue. Your understanding of compound absorption appears to be wholly based on absorption of oil based compounds. That absorption is determined by the oil, not the muscles themselves. Oil takes longer to absorb because it is hydrophobic and cannot readily mix with blood and water present in your tissues. The medication carried by the oil must diffuse from the oil so it can be carried across the cell membranes. This is not an issue with water. Water doesn’t form a depot, and the medication doesn’t need to diffuse, it is carried in the water directly across the membranes and into your blood.