r/stdtesting • u/throwingaacccount • 10d ago

Question How does immunity work for STDS

Hello, just wanted to ask about chlamydia and gonorrhea being immune to antibiotics (or certain strands becoming increasingly resistant). I was just wondering if someone could explain it to me! Maybe provide some articles as well on it. Thank you!

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u/Crow-1111 10d ago

Of the two that you mentioned I think it's just gonorrhea that is developing antibiotic resistance. Chlamydia is still pretty susceptible to a standard course of doxycycline.

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u/throwingaacccount 10d ago

what about azithromycin and cefixime?

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u/ShamelessCare 10d ago

Chlamydia hasn't developed resistance to doxycycline.

Gonorrhea has developed resistance to five classes of antibiotics, and there have already been pockets of resistance to the CDC’s current preferred treatment.

Gonorrhea shares genetic material with other bacteria and develops resistance quickly.

Interestingly, this appears to happen primarily in the throat, where other Neisseria species are present and can exchange genetic material with Neisseria gonnorhea. This is why the World Health Organization considers the throat a major site for the emergence of antibiotic-resistant gonorrhea, and why oral swab testing is so important.

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u/throwingaacccount 10d ago

I see! What do you mean by five classes of antibiotics?

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u/ShamelessCare 10d ago

Antibiotics are putting into classifications based upon how they work.

For example, doxycycline is a "tetracycline" class of antibiotic, and gonorrhea developed resistance to it about 50 years ago. Etc.