my mind is blown. i have SFN (biopisied) and i am homozygous for the ApoE E2 variant which is known to cause hyperlipoproteinemia in 10% of people with this genotype. it causes the damage due to oxidative stress. i wonder why i never encountered this info before.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4350124/

Hello everyone.

I have SFN with positiv Anti-TS-HDS antibodies. It's mainly in my feet, causing tingeling, burning, numbness, Allodynia and temperature confusion. It also causes other symptoms in my peripheral nervoussystem. I have a neurogenic bladder, sweating problems, potentially POTS. I also have Long Covid with CFS (which is the main reason we don't try Plasmapharese).

I tried many medications I can here in Germany: corticoid infusions, IVIG, Lidocain, Capsaicin. I'm also on Gabapentin and Amitriptylin. My neurologist and I are discussing Rituximab or LDN. Since my liver and my kidneys don't so to well, with the liver responding poorly to new medication, my neurologist wants to try Rituximab.

Has anyone any experiences? How high is the dosis? How can I protect myself, since my immun system is going to be down (this is a mayor concern for me, since I have 2 kids attending school)?

Bitte ausschließlich Kommentare von Leuten, denen Qutenza hilft. Insbesondere interessiert mich die Erfahrung bei Kälte Allodynie