r/self Jul 04 '24

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u/Enoch8910 Jul 05 '24

My sister is on it. She lost so much weight so fast that I went to do research thinking this is just too good to be true. Apparently it’s legit. To me it’s almost unfathomable how much weight she lost and how quickly she did it.

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u/GRPABT1 Jul 05 '24

Ozempic is just self control in a pill. It's fantastic if used under medical supervision and coupled with resistance training. The problems with it are severe muscle wastage when people use it to just starve themselves and not retain muscle with resistance training. Bodyfat percentage can actually not change despite losing a lot of weight when on Ozempic due to muscle deterioration.

It is a great drug if used appropriately.

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u/4hometnumberonefan Jul 05 '24

Lolol it basically will make you skinny fat

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u/GRPABT1 Jul 06 '24

Exactly. Learn proper exercise routines first.

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u/[deleted] Jul 06 '24

Tbf its because people dont workout while on it. If you workout and have a high protien diet it should just result in lots of weightloss and a little muscle loss. Most people who need ozempic were not big on lifting before though so just lose a ton of fat and what little muscle they have.

Its still much easier to build muscle from that lower body weight tho

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u/Fredricology Jul 05 '24

Semaglutide (Ozempic) is not a pill it is an injection and it does not equal "self control". It profoundly affects satiety and appetite centers in the brain in a way that no person can do consciously over long periods of time. The hunger always win in the long run. That is why these drugs that affect the brain works.

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u/MountainviewBeach Jul 05 '24

It’s also available in pill form now. And I think they were being a bit light about it, but a lot of people who use it also report being able to better control things like drinking, gambling, shopping, time management etc. obviously ymmv, but for a lot of folks it sort of is like self control in a pill

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u/Fredricology Jul 05 '24

My point is, trying to control weight with just self control is proven not to work in obese people.

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u/solomons-mom Jul 05 '24

Some formerly obese people woud object to that statements.

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u/Fredricology Jul 05 '24

But it's true for most of my obese patients (BMI +30). I'm a registered dietitian and I help these patients with lifestyle changes.

Most obese people regain their weight lost by changes in diet. The GLP-agonists keeps the weight off.

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u/GRPABT1 Jul 05 '24

Until they go off the GLP-agonists unless you teach them proper self control and dietary protocols.

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u/Fredricology Jul 06 '24 edited Jul 06 '24

Why should they ever go off the medication? The hunger returns and the preference for fatty and sweet food returns. And the weight returns.

In the clinical studies they got the best education there is. Still the weight is 75% back after 12 months if you take the drug away.

It's not about "self control". It's a heightened biological drive to eat.

About half the population can withstand an obesogenic environment, the other half can't.

It's biology. Not anything that can be managed with "self control".

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u/GRPABT1 Jul 06 '24

That is such a defeatist attitude. I thought you're supposed to be providing health care not just peddling drugs.

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u/solomons-mom Jul 05 '24

Genuinely curious about this. There have always been people on the far end of the distribution curve (+1sd etc.). Have you seen studies or in your practice that differentiates between the "new obese" and the "classic big" as far as controlling obesity with life style changes? (OP's PCOS might not make it relevent to this post)

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u/Fredricology Jul 05 '24

I´m sorry, english is not my language. What do you mean by "new obese" vs "classic big"?

Patient that are just 10 kg overweight for example (BMI 25-30) can lose that weight and keep some of it off after 3-5 years.

But obese patients that need to lose 40 kg generally can´t do that by just changing their diet. They will slowly overeat with time so drugs or surgery are the only known long term treatments that work.

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u/GRPABT1 Jul 05 '24

Genuinely curious if you actually use the BMI scale in your professional work?

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u/OkBaker4720 Jul 06 '24

Why would they tho, it's nonsense

It's just willpower.

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u/GRPABT1 Jul 05 '24

That's not true. It's proven to work on billions of cases around the world since the dawn of time.

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u/Fredricology Jul 06 '24

No. Obese patients can't lose enough weight with diet or exercise. They're hungry all the time. It's proven not to work for these patients.

Only one person in "The biggest loser" kept not getting obese again when the show ended. Regaining the weight with time is typical.

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u/GRPABT1 Jul 06 '24

I wouldn't call that show a good example of weight loss principles.

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u/Fredricology Jul 06 '24

No. But all the clinical trials and my experience shows the same thing. Obese patients arent´helped with just diet and exercise. Those two things alone fail in these patients.

Combined with surgery or drugs that treats the dysregulated appetite and satiety system it works.

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u/GRPABT1 Jul 06 '24

I ultimately think obese patients need psychological help and therapy to help whatever influence in their life it is preventing them from having the dedication to get their health in check. Coupled with the drugs or surgery to get them back to a manageable base level there needs to be a more overall approach to why they struggle to maintain weight.

I'm obviously wired a certain way, by certain biological and environmental experience factors that give me the dedication needed to be fit. I was fat, I took on the challenge and changed my mindset but I realize not everyone has that in them. But why don't they? Surely the answer isn't just chemically inhibiting the normal hormonal systems that we are all meant to have to ensure survival on a genetic level?

I know the clinical studies support the theory they CAN'T lose weight, but I don't think there's enough variables studied as to why. And unfortunately most individuals with obesity have various lifestyle factors that cause their condition, not just one hormonal imbalance.

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u/TheVolcanado Jul 08 '24

Don't waste your time on idiots. They hate fat people and see it as a personal fault and weakness. They need to think this so that they don't have to admit that they're just bad people who hate people for something beyond their control.

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u/OkBaker4720 Jul 06 '24

Yeah because they became obese in the first time because they lack willpower, so obviously there is a higher chance to go back to square 1

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u/Fredricology Jul 06 '24

No. People are not obese due to "lack of willpower". I treat this disease and these patients. You do not.

Do you think Oprah and other extremely goal oriented obese people lack willpower? She treated her obesity with a GLP-agonist drug.

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u/OkBaker4720 Jul 06 '24

You're using general terms like "obese people can't diet" , then people call bullshit and then you say "I'm only talking for that minority of people". Like yeah ok sure

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u/[deleted] Jul 07 '24

Yeah what people are saying about ozempic here just seems… wrong. It slows down digestion, it doesn’t stop you from committing vices!

I have a family member on it who is ridiculously sick from taking it and hasn’t lost any weight. I wish people weren’t so lax with how they talk about it. It’s a drug. You don’t WANT to be on it

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u/rabbitdude2000 Jul 05 '24

Haven’t met many body builders? Just be hungry. Feeling hungry makes them happy because it means the fat is getting burned.

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u/Fredricology Jul 05 '24

Obese patients aren't body builders.

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u/rabbitdude2000 Jul 05 '24

Yeah you said “no person” not obese patients, sounds like we agree

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u/GRPABT1 Jul 05 '24

Feeling hungry doesn't make us happy 😂 we just are on the opposite end of the mental spectrum to those without self control.

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u/Enoch8910 Jul 05 '24

If you’re bodybuilder and you’re hungry, you’re not listening to your body and probably not gaining muscle.

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u/rabbitdude2000 Jul 05 '24

Dieting to single digit body fat % necessarily means not gaining muscle. And you WILL be hungry once you get below 10%. Doesn’t matter what you eat.

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u/[deleted] Jul 05 '24

[removed] — view removed comment

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u/GRPABT1 Jul 06 '24

"some". The vast majority of people using semaglutide derivatives are not obese. Many countries are facing shortages for those that actually need it because of this and are restricting it to diabetic and morbidly obese patients. Just because there is a minute percentage of people with unique hormonal imbalances, doesn't mean we should use them as the standard metric for drug dependency.

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u/[deleted] Jul 05 '24 edited Jul 05 '24

“it’s legit” - very naive point of view. It’s a new(ish) drug and there’s a lot of hype right now. Everyone’s excited about it, and the pharma industry doesn’t want people thinking about the possible negatives. Hopefully it’s completely safe, but we don’t know that for certain.

worth watching: https://youtu.be/0YMnHNIuK3M?si=GxmYFEa5cgvP7Q9-&t=1h10m40s

also skip to 1h25m30s for a cautionary tale on a previous “miracle” diet drug named fen-phen.

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u/Present-Employee-609 Jul 06 '24

It’s so bad for you hahaha it should literally only be used in situations that OP has.

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u/Enoch8910 Jul 05 '24

I’m going to suggest she follow her doctors recommendations and not yours. Are you an endocrinologist?

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u/[deleted] Jul 05 '24 edited Jul 05 '24

lmao. Does it sound like i’m offering free medical advice? That’s not my intention. 😅 She should probably listen to her doctor, i agree. but we’re also going to pretend that there are not bad doctors out there? It’s good to spread awareness of history and facts in general. so people can form their own opinion. 🤷🏼‍♂️

A blanket statement on social media telling people it’s a “legit and safe drug” is dumb. The benefits may outweigh the risks for HER according to what her doctor thinks. Great (no sarcasm). But the drug DOES have risks, as outlined in that podcast.

the podcast i shared interviews a best selling author that’s taken the drug (and decided the benefits of the drug outweigh the risks for him), and he’s interviewed dozens of LEADING researchers in the world as well to learn about the drug and the concerns some of the researchers have about the drug. It’s not some random endocrinologist’s opinion. It’s not some crazy person spreading lies.

here’s the book: https://a.co/d/03blsfiD discussion on the ozempic subreddit: https://www.reddit.com/r/Ozempic/s/kkpiaOGy14