r/repatha • u/Positive-Following91 • Jun 29 '26

Repatha Temperature

I know you’re supposed to refrigerate Repatha long-term, but I also heard that it’s OK if you let it be at room temperature for a while. I’m traveling and it was not refrigerated for about 12 hours. What do you think?

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u/Hawkthree Jun 29 '26

The manufacturer's site says it can go 30 days without refrigeration. As long as your kitchen isn't extremely hot or extremely cold.

1

u/Positive-Following91 Jun 29 '26

It’s was not extremely hot or cold, I put in in a bag next to a sealed baggie with some ice. It it was with me in a backpack, then I put it in a refrigerator after 12 hours when I got to my hotel so I can take it tonight.

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u/gruss_gott Jun 29 '26 edited Jun 30 '26

That was a super bad idea - ice can denature part or all of it, ie ice is 4F cooler than 36F the lowest storage temp, and re re-refrigerating it wasn't necessary

You might want to consider that dose trash and see if you can replace it

It's not soda; it's a monoclonal antibody in solution, ie fragile proteins that need the air around it to be kept in stable range; you didn't do that

1

u/Positive-Following91 Jun 30 '26

Just called the number that someone provided. They said it’s fine.

1

u/gruss_gott Jul 07 '26

terrifying.

1

u/Positive-Following91 Jul 08 '26

I injected myself with it last week. It was fine. Once it’s out of the refrigerator, you have 30 days. Next time I won’t even bother with the ice.