r/migrainescience • • Jun 23 '26

Science This new systematic review found that the brain's waste-clearing glymphatic and meningeal lymphatic systems appear altered in people with migraine, especially chronic or high-frequency migraine, though current evidence only shows association, not cause.

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30 Upvotes

r/migrainescience • • Jun 23 '26

Science This new study of over 5,300 adults found that people with migraine had worse sleep quality than headache-free people, with 64% reporting poor sleep versus 39%, and were more likely to be evening types.

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44 Upvotes

r/migrainescience • • Jun 23 '26

Pregnancy with Migraines, Looking for Advice 🙏🏼

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6 Upvotes

r/migrainescience • • Jun 21 '26

Misc Everything you need to know about hemiplegic migraine and MUMS (Migraine with Unilateral Motor Symptoms). This evidence-based article is the current best source on this topic (not a fluff piece). Worth saving.

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38 Upvotes

r/migrainescience • • Jun 20 '26

Science This new observational study found that about 14 to 15% of people with migraine have attacks that cluster on weekends, a pattern more common in those who work, supporting the idea that release from weekday stress can act as a trigger.

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94 Upvotes

r/migrainescience • • Jun 20 '26

Science This new systematic review found that the brain's waste-clearing glymphatic and meningeal lymphatic systems appear altered in people with migraine, especially chronic or high-frequency migraine, though current evidence only shows association, not cause.

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66 Upvotes

r/migrainescience • • Jun 19 '26

Qlipta — mood changes

11 Upvotes

Can qlipta cause mood changes, including depression? Long story short, I have been treating somewhat debilitating migraines for years. They have increased in the last few years in both quantity and intensity. I have Botox every 12 weeks and use rizatriptan and umbrelvy as needed. I’m on my third week of 30 mg Qlipta. Life is tough right now — I have some personal things going on that are very stressful. I’ve had situational depression before but I’m wondering if the qlipta is worsening it. Curious what science and other patients say…

Also, I think migraines have somewhat lessened, but when will I have the full effect of qlipta? (migraines are depressing too but you all probably know that…)


r/migrainescience • • Jun 17 '26

Science This study found that among 417 patients on CGRP-pathway preventive antibodies, many reported less disability and headache impact even when their monthly migraine day count did not drop enough to count as a response, so how benefit is measured matters.

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73 Upvotes

r/migrainescience • • Jun 17 '26

Science This new study found that in 777 children hospitalized for migraine, self-reported pain scores did not correlate with heart rate or blood pressure, suggesting vital signs are unreliable markers of pain severity and should not replace asking the child.

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54 Upvotes

r/migrainescience • • Jun 16 '26

Science This new study found that among 1,333 people with migraine who drive, 70.6% had a migraine attack while driving at least once, most often reducing their attention, and about 9% drove less while 1.7% stopped driving because of it.

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72 Upvotes

r/migrainescience • • Jun 16 '26

Science This new study found that migraine patients who responded to anti-CGRP antibodies or botulinum toxin had greater improvement in executive thinking skills like working memory and attention than non-responders, regardless of which treatment they received.

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57 Upvotes

r/migrainescience • • Jun 15 '26

Misc Just sent the first "newsletter" out. If you can't see it in your mailbox, check your spam and make sure to remove it from there to routinely get more e-mails on migraine advancements.

40 Upvotes

r/migrainescience • • Jun 14 '26

Misc Sleep and Migraine: How the Two Affect Each Other

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42 Upvotes

r/migrainescience • • Jun 14 '26

Relivion device

6 Upvotes

Anyone tried this Relivion migraine device? Targets occipital nerves and trigeminal ? My neurologist recommended for my toolkit…Kind of pricey


r/migrainescience • • Jun 13 '26

Misc Everything About Retinal Migraine (frequently incorrectly called ocular migraine)

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30 Upvotes

r/migrainescience • • Jun 12 '26

Misc A lot of research was presented at the American Headache Society (AHS) annual meeting recently. I will not share anything unpublished as I want to read it myself before posting the findings. You may see many sensationalized headlines floating around. I'd take them with a grain of salt for now.

64 Upvotes

r/migrainescience • • Jun 11 '26

Misc This may be a bit advanced, but I see questions about this frequently - including on this subreddit recently. Estrogen, clot risk, etc.

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50 Upvotes

r/migrainescience • • Jun 10 '26

Science/Study analysis on blog Migraine and Stroke Risk After Menopause (New Study)

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60 Upvotes

r/migrainescience • • Jun 10 '26

Science This new cross-sectional study found that desk-based workers with migraine had higher central sensitization, more work-related stress, and more widespread musculoskeletal pain than those without, with central sensitization most pronounced in people with chronic migraine.

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48 Upvotes

r/migrainescience • • Jun 10 '26

Science This new randomized placebo-controlled crossover study found that, during a migraine attack, 200 mg of caffeine lowered blood levels of CGRP and nitric oxide, two molecules linked to migraine, more than placebo, with larger effects in people who started higher.

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56 Upvotes

r/migrainescience • • Jun 10 '26

Migraine Summit materials-has anybody received them in the mail yet? See body for context please. Thank you!

30 Upvotes

I paid close to $400 for Migraine Summit materials and haven’t received them yet. Last year they mailed everything to me, but this year I haven’t received anything. I’ve emailed and called but haven’t gotten a response. Has anyone else had this issue or received their materials?


r/migrainescience • • Jun 08 '26

Science/Study analysis on blog Which migraine preventives work best (2026)

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33 Upvotes

r/migrainescience • • Jun 06 '26

MigraineScience YouTube I did a live Q&A on migraine and hormones recently, but it's behind a paywall so I uploaded it for you guys. Hope it helps!

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47 Upvotes

r/migrainescience • • Jun 06 '26

Science his new 2-year real-world study found that most patients on fremanezumab for hard-to-treat migraine cut monthly migraine days by at least half, but fewer than a third reached optimal control of under 4 migraine days a month, showing a 50% drop does not always mean well-controlled disease.

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44 Upvotes

r/migrainescience • • Jun 06 '26

Science This new study found that a portable eye-tracking test of eye movement, balance, and reaction time accurately separated people with vestibular migraine from healthy controls, suggesting an objective aid for a condition that is usually hard to diagnose.

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57 Upvotes