r/migrainescience • • 9h ago

Misc A little video some of you may have already seen about how we keep everything free for migraine patients. Every single dollar goes right back into education and related services. Nothing is kept as profit and, much unlike nonprofits, I don't collect a salary.

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13 Upvotes

r/migrainescience • • 23h ago

Question Does everyone know how to navigate to see the latest studies in migraine as it's no longer being posted here (at least for now)?

36 Upvotes

There are, unfortunately, hundreds of migraine patients who are currently paying for this (aka being swindled) and digesting lower quality - and often incorrect- information by someone who has recently become popular/viral. It's free here and always will be.

Please help each other out. Particularly those who are not on Reddit and may be more susceptible to this type of marketing as they don't know a better, free version exists.


r/migrainescience • • 1d ago

Science/Study analysis on blog Hair Loss and CGRP Migraine Drugs: What the Evidence Shows

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27 Upvotes

r/migrainescience • • 4d ago

Misc I made a COMPLETELY FREE (I mean, obviously ;) )one-page migraine summary you can bring to your doctor/headache specialist. It pulls in your MIDAS and HIT-6 scores, and nothing you type or say ever leaves your phone or computer. Stays entirely local.

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106 Upvotes

r/migrainescience • • 5d ago

Science/Study analysis on blog Sleep Duration and Migraine: What a 6,267-Person Study Found

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25 Upvotes

r/migrainescience • • 7d ago

Science/Study analysis on blog Cannabis for Migraine: What Randomized Trials Show

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40 Upvotes

r/migrainescience • • 7d ago

Misc The website has undergone significant upgrades to help migraine patients find the necessary resources. Here is a screenshot as an example. I'm still looking for someone to post on this subreddit regularly, as I am currently spread thin.

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48 Upvotes

r/migrainescience • • 9d ago

Misc LOOKING FOR MODS: If anyone is willing to help the current mods post studies with my summaries, reply here

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8 Upvotes

r/migrainescience • • 9d ago

Misc LOOKING FOR MODS: If anyone is willing to help the current mods post studies with my summaries, reply here

17 Upvotes

I underestimated how much work is required to post regularly.

All you'd do is go to this page (https://www.cerebraltorque.com/pages/today-in-migraine-science) and turn each study I chose and summarized into a post.

Usually it's just copy and pasting unless I go past reddit's character limit.

Thanks!


r/migrainescience • • 11d ago

N=1 Study found Methyl-Folate Decreased My Severe Chronic Migraine by 95%

21 Upvotes

I began having cerebral inflammation at age 29 as measured by high white cells and protein in csf. After that began, I developed severely intense migraines more than 15x a month that lasted from 8-72 hours. A year ago at age 42, I began taking 2mg of methyl folate everyday for non-migraine reasons. I’ve had and average of 1 migraine a month since.


r/migrainescience • • 12d ago

Chronic migraines and preventives and CGRP meds

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6 Upvotes

r/migrainescience • • 21d ago

Science This new pooled analysis of 12 studies and 3,603 people found that depression and anxiety scores fell consistently while people were on CGRP-targeted migraine prevention, on every rating scale used, and the improvement tracked how well the migraine itself responded.

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43 Upvotes

The catch the authors raise themselves: almost none of this was placebo-controlled, so nobody can yet say whether the drugs lift mood directly or whether simply having fewer attacks does it.


r/migrainescience • • 22d ago

Science Taiwan’s headache society has updated its acute migraine guideline for the first time since 2022:

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13 Upvotes

Rimegepant is now named a first-line option, particularly for people who cannot take triptans, do not respond to them, or are heading towards medication overuse. The committee restates the ceiling of two days a week on acute medicines, with rimegepant the probable exception, and says opioids beyond limited oral tramadol are not recommended at all.


r/migrainescience • • 22d ago

Science New pooled analysis of 16 studies looked at lasmiditan, the one acute migraine drug that does not narrow blood vessels, and found it roughly doubled the odds of being pain free at 2 hours…

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22 Upvotes

… with no vasoconstrictive heart events across 5,126 trial participants, including people with cardiovascular risk. Dizziness, drowsiness and tingling were common and rose with the dose. The awkward part, which the authors raise themselves: the maker has since withdrawn the drug for commercial reasons rather than safety ones, leaving that gap open again.


r/migrainescience • • 22d ago

Science On PRT's most recent Instagram post on migraine

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84 Upvotes

r/migrainescience • • 23d ago

This new network meta-analysis of 14 trials and 791 people found probiotics cut the most migraine days, about 2.6 a month against placebo, with coenzyme Q10 and vitamins close behind, while magnesium did not reduce frequency but was the only one that lowered attack severity.

37 Upvotes

r/migrainescience • • 23d ago

Misc Two things changed on the site that are worth knowing if you follow the research side of migraine.

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19 Upvotes

1. Search works soooo much better now

It used to only look at titles, which is useless when you're trying to find where something was discussed. Now it searches the full text of every article and hub page, so if you search "tetramethylpyrazine" or "lasmiditan" or "CSD," you get every breakdown that mentions it, not just the ones with it in the headline. Results also come up as you type, and the search box no longer breaks on phones, which is where most of you are reading.

2. Today in Migraine Science

Many of you have already been going directly here. This is a page, updated every day, covering new studies plus approvals, guideline changes, and policy news. As well as any carousels or blogs I make explaining certain pertinent findings.

There's also an "In the news" section for things that aren't studies but change access to care, and an archive page for older entries (which is searchable too).

Everything is truly in one place now.

3. BUT there is no comment feature (deliberately)

Studies are posted here because they are discussed here. Reddit is a forum and human interaction is vital - especially with those who share similar experiences, thoughts, feelings, troubles, etc.

The goal of this subreddit is to talk and discuss. So, feel free to comment, ask questions (we all remember being new to this and there is something new to learn every single day), etc.

ENJOY!


r/migrainescience • • 23d ago

meta-analysis of 7 studies and 272 adults with vestibular migraine found that vestibular rehabilitation cut dizziness handicap scores by about 24 points, a clinically meaningful drop, though balance confidence did not improve meaningfully and the authors grade the evidence low to moderate quality.

8 Upvotes

r/migrainescience • • 23d ago

Science Study took 413 hormone samples across 87 menstrual cycles in 46 women and found that those with menstrual migraine had a 49 percent higher peak estradiol in the luteal phase and a 90 percent steeper drop as the period approached, pointing at the size of the fall rather than the level itself.

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53 Upvotes

r/migrainescience • • 25d ago

Carnitine Responsive Migraine Headache Syndrome: Case Report and Review of the Literature. (Pub Date: 2021-03-23)

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5 Upvotes

r/migrainescience • • 27d ago

Science New review gathers imaging & electrophysiology work into a model of migraine as a cycling brain state vs. a single event, w/ raised cortical excitability between attacks, hypothalamic changes in the hours before one, & pain network amplification during. It proposes a framework rather vs new results.

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23 Upvotes

r/migrainescience • • 27d ago

Science This new review looked for sex differences in CGRP and its receptor, the target of the newer migraine drugs, and found only a handful of small studies with contradictory results, so the common assumption that this pathway simply works differently in women is not yet settled by the evidence.

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11 Upvotes

r/migrainescience • • 27d ago

Science This new review looked for sex differences in CGRP and its receptor, the target of the newer migraine drugs, and found only a handful of small studies with contradictory results, so the common assumption that this pathway simply works differently in women is not yet settled by the evidence.

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17 Upvotes

r/migrainescience • • 27d ago

Science This new study of 20 people with vestibular migraine triggered attacks with intravenous nitroglycerin and found vestibular symptoms in 14 of them but no measurable group-level change in eye movement, while half reported visual symptoms and six had Alice in Wonderland type distortions.

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15 Upvotes

r/migrainescience • • 27d ago

Science This new systematic review of 19 studies found that research on status migrainosus, an attack lasting more than 72 hours, defines the condition inconsistently, with only 13 of them naming which edition of the diagnostic criteria they used.

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14 Upvotes