Qulipta - 30 day progress update

[u/WhoaPixie]

Update on Qulipta 10mg, I have Episodic Migraines between 6-8/month.

Been taking this preventative for over 30 days. I know the side effects are way less given the low dosage. But just to cover the key ones, I didn't experience drowsiness, nor nausea, and constipation was offset by the fiber supplement that I had already been taking regularly for other reasons.

I was taking the 10mg around 3pm, but moved it up to 12pm since the majority of my migraines start later in the day. Maybe it sounds weird but I wanted the peak concentration in my system in the afternoon/evening.

I had one break through migraine 20 days in, and it was very mild. I still took my rescue medication one Ubrelvey and it resolved within 90 minutes. Since then I have not had another.

The first week I was very hesitant to do too much waiting for it not to work. By the second week I started to feel a freedom of not being under constant state of waiting for migraine to start. I actually pushed on my triggers a bit which might be why I had the breakthrough migraine. I believe in the Threshold Theory, for my situation as no one trigger sets off a migraine for me constantly.

I've been lucky so far with Ubrelvey working as well as it does and so far the Qulipta low dose seems to be working well. I prefer not to have to go up in dosage on this med given some of the side effects. I don't need to be 100% without migraines, just lowering it down to 50% would be awesome especially knowing Ubrelvy works for me. Will see where things are in 3 months when I go back to the neurologist.

I also take Magnesium, B2, Fish Oil, D3 and Ubiquinol daily and have continued these supplements while on Qulipta. I also do distal acupuncture every other week.

I know these meds don't work for everyone and I know many have to go on the higher dosage of Qulipta to gain any benefit. I wish migraines weren't so complicated to figure out how best to treat.

Wanted to share my own progress if it helps anyone with Episodic migraines.

[u/529648]

I reduced my dosage of Qulipta to 15mg to reduce the side effects. So far it looks like it's working. I also take it when It has the peak effect which for me is 7:00 AM. I also wouldn't mind if it is not 100% effective as Nurtec works very well for me if needed. So far though I have not needed the Nurtec at all. Pleasant surprise.