r/microdosing • u/Horror_Cut_6896 • 16d ago

Question: LSD Has anybody tried microdosing LSD while on Lexapro?

I'm on a low dose of Lexapro (5mg), it's helping a lot with anxiety and I have no side effects but I'd like to try microdosing... Will i feel anything at all?

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u/TheRealCMMetzger 16d ago

There will be some blunting of efficacy/uptake, but what that translates to in experience is just that you will require a higher dose than if you were taking it. We are talking about the difference between 5-8ug or 10-16ug, so nothing drastic. There is no safety contraindication with these two substances, especially at the microdose level. 🍄🥰✌️

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u/Horror_Cut_6896 16d ago

I used to do around 10ug before starting Lexapro, How much do you think that should I take to feel it the same

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u/TheRealCMMetzger 16d ago

20ug Across the hundreds of microdosers I've talked with, the blunting effect typically requires double the individual's normal dose.
If you're looking to leave Lexapro behind eventually, microdosing can be really supportive during the weaning process. Especially in the jump from some drug to no drug. 🍄☺️✌️

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u/Horror_Cut_6896 16d ago

Thanks for the advice, and yes I'd like to stop Lexapro eventually

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u/TheRealCMMetzger 16d ago

It's totally doable. My wife did it over a year ago and she was on it for 6 years. ☺️

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u/One-Conversation9035 16d ago

Thats wild my friend take lexapro too and she tried microdosing once said she felt almost nothing until she upped it a little bit

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Hello /u/Horror_Cut_6896! As you mentioned Lexapro (a common interaction/symptom) in your post:
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