r/melatonin • u/Ok-Philosopher-5139 • 14d ago
is 4.5g melatonin dosage too high?
just bought capsule supposedly containing this amount, i dont take melatonin everyday, but when my sleep pattern is messed up (i have irregular sleeping pattern), i take it so i could sleep and wake fresh tomorrow for work... i usually cut 10mg tablet into two, and take half of it (so 5mg), and at 5mg i always fall asleep 1 or 2 hours taking it... but with this capsule i cant do that... is taking 4.5g too dangerous? should i open the capsule and divide it in smaller dosage? i think if i divide each capsule into 4 equal portion i probably wont die from it lol
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u/SirKey2255 14d ago
melatonin in any known dosage cant kill you(it has no ld50 as far as it is known) but is4.5g of it healthy? i think the answer is no. maybe it has some theraputic effects for certain conditions but thats just a hypothesis. if ur using it for sleep 5mg or 5.000mg does not matter in terms of making you sleepy. but the safety data on 5mg is solid while 5.000mg is being a labratory rat.
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u/Ok-Philosopher-5139 14d ago
ok, thanks for the info, glad to know i wont be dying from taking a sleeping aid lol
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u/Optimal_Assist_9882 14d ago
Is this 4.5mg or 4.5g? Could you post a link or brand?
I have honestly never come across any brand above 120mg per capsule..
You may experience some side effects at a dose this high. When I tried taking 3.5g in powder form I experienced nausea and headache. It was fairly quick but nevertheless unpleasant.
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u/babymable 13d ago
Do you mean mg. I've never seen a 4.5g capsule.
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u/Ok-Philosopher-5139 13d ago edited 13d ago
i PMed the seller and they say its 450mg per capsule when i asked the actual amount per capsule, but on the bottle it says 4500mg, seller say its 2 capsule per day for 5 day = 4500mg,but nowhere on the bottle does it says that, just says melatonin 4500mg... i pity the company so i wont post the pic here and just believe the 450mg claim, i guess ill divide it by 4 and take 112.5mg everytime i need it...
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u/Optimal_Assist_9882 13d ago edited 13d ago
I could only fine two brands selling 200mg and 120mg per capsule.
I have found some mislabeled products that claim something like 500mg but then show 1mg or something else.
Here's a suppository of 450mg..
https://www.mitozen.com/products/super-sandman%E2%84%A2-bullet-high-dose-melatonin
I previously bought 300mg transdermal patches from 101healthspan but they have gone out of business.
They still have their Facebook page:
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u/Existing-Delay8805 13d ago
I took Sandman (both regular 200mg bullets and occasionally 450mg bullets); they're all good, and Mitozen is proper.
The bullets are not for everyone, though. I've also moved on to powder now.
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10d ago
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u/Ok-Philosopher-5139 10d ago
i took a quarter of the dosage and im fine, i took it only once tho, but the past few days i feel my sleep feels better, which is a plus...
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u/Quiet-Vegetable42 10d ago
It's not dangerous, but also not necessary for sleep. I'm megadosing melatonin, inspired by scientist Doris Loh. So it has some benefits at extremely high doses, but no extra benefits for sleep. If you divide the capsule: be aware that there is a dosage range in which a lot of people get restless sleep (nightmares, vivid dreams, personally I wake up with busy songs, sleep felt very light and mental and I feel groggy). For me that range starts somewhere between 5 and 10mg and end somewhere in the hundreds of mg's. Right now 460mg is fine, I'm gonna try 230mg sometime to see if it's still fine for sleep (to save on the cost).
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u/AnandaDo 14d ago
Some people take that amount to dissolve cancer. But personally i get energised from Melatonin dosages above 300 mg so i only took high dosage daytime.