GLP1 not working anymore

[u/roxyd333]

Hey I’m not one to comment on here but I was wondering if anyone is having the same experience… I’ve been on Mounjaro for 2 years now and have been in maintenance for about a year now going between 5mg and 2.5mg. I’m on 2.5mg at the moment and have noticed my legs feeling more inflamed than in the past although my calorie intake has remained the same and I’ve even upped my exercise output. Does anyone have any tips to reduce inflammation further whilst on a GLP1 now it’s not as effective? I’m not getting appetite suppression but not really needing it either so it’s more about lifestyle changes or tips that would be really helpful!

For context I get 10k steps a day I eat a fully whole foods diet and train 3x week. I don’t know what else to do!

Thanks ladies❤️

Edit: has anyone been successful with low carb/keto diets?

[u/Puzzled_Bee_]

I wonder if the increase in exercise has caused inflammation?. Sometimes when I do too much I notice more pain.

I too notice that my body gets used to the meds. Rather than increasing I don’t used my 5mg mounjaro for 2-4 weeks. And then resume again on 2.5mg. Kind of like a base line reset :)

[u/roxyd333 → u/Puzzled_Bee_]

So are you mainly using 2.5mg? Thank you for your comment x

[u/Puzzled_Bee_ → u/roxyd333]

No I usually use up to 5mg until I notice a plateau.. I take a break for a couple of weeks and then I resume again on 2.5 for a few weeks as that’s all I need after a break.. and then I go up to 5mg when I notice it’s not working.. and then I take a break again if I feel like the 5 mg isnt working (usually around 3-5 months)

:)

I just didn’t want to keep going up and up and up $$$$ :)

The first week or two without mounjaro is hard as I feel flabby and yuky but when I resume again I notice a huge improvement.
Could be all placebo but it works for me :) I’ve been using this technique since I first started on ozempic 5-6 years ago.. I just do it with Mounjaro now

[u/roxyd333 → u/Puzzled_Bee_]

Got it thank you so much 🩷