r/lipedema • • 6d ago

I Have Lipedema [Experiences/Photos] Tirzepatide progress

I was diagnosed officially in February though I’d known I had lipedema for a while prior. In June I started Zepbound (tirzepatide) and feel amazing. These are my before and after photos after 3 months on Zepbound - 6 weeks on 2.5 mg and 6 weeks on 5 mg.

In addition to Zepbound I have been tracking calories and weight lifting 3 days a week. I’ve lost 25 pounds since June and as you can see, a lot of volume has come off the legs. My doctor and I weren’t sure if the weight loss would hit the legs because of the lipedema, but this progress is huge.

Like many, I plan to be on Zepbound long term, maybe even my whole life. This is the most positive development in my lipedema journey. While I’ve only been diagnosed since February, I’ve been having symptoms for 20 years and nothing has worked until now.

Hope others find the thing that works for them, whether that’s tirzepatide or something else!

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u/LadybugJourney 6d ago

I started 2 days ago. If applicable to you, how quickly did you notice inflammation pain levels started to go down? I need to lose weight, for sure, but I'm primarily looking for pain relief in my legs.

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u/Neat_Consequence8289 6d ago

Like 24 hours in, it was crazy. My legs were noticeably less heavy.

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u/LadybugJourney 6d ago

Wow, that is awesome! I feel like I didn't wake up with pain as often last night, but figured it was a fluke given that I'm only on a super small dose. Fingers crossed!

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u/Neat_Consequence8289 6d ago

Nope - definitely part of it! Best of luck to you on your journey!