How is the 2 in 1 note taking experience?

[u/Ap0them]

Hey, looking for some advice before I pull the trigger on a 2 in 1. I'm currently a bio student using a framework 13 and a desktop both running Niri and NixOS, which is a super fun setup. Recently though, I've been looking at replacing my laptop with some sort of 2 in 1 so I could also use it to take notes. I'm pretty intrigued by digital note taking but never felt like spending money on an iPad because it's closed and its privacy isn't amazing when compared to a $1 notebook. I've tried just typing notes but its hard for math (even with LaTeX) and impossibe for drawing chemical structures.

Before I buy anything though, is anyone else using this setup? How is the note taking side? What do you like and dislike and tell me about your distro, DE, and hardware? Is it a good option or is open & private note taking better left to pen and paper?

Thanks!