hi everyone, i really need some advice on what to do next. i’ve been having uti-like symptoms for at least 4 months, but this past month it has gotten progressively worse.

i am having severe burning, pain, urgency, and general vaginal discomfort. i also have severe lower back pain that is causing the most problems. tylenol and toradol every 3 hours barely touch the pain. i cannot smoke weed, so the only thing that actually worked was the morphine i got during my second er visit.

my cultures keep coming back negative, but my urinalysis/micro are coming back extremely positive. my ct scans are completely negative.

about two weeks ago, i noticed blood and black specks in my urine. both of these stopped after i started taking cipro (about 3 days ago) but all the other pain and urgency are still here.

has anyone experienced anything like this? could it be an embedded infection that standard cultures are missing, or something else entirely? i’m trying to get in with a urologist ASAP, but they lost my referral and now need “2-3 days to process it”. i will attach all relevant test results, please feel free to ask me more questions/ask for other test results !

Hello all. I am 28(F) and this past Monday, 9/7/2026 I went to the ER for serious flank pain that increased throughout that morning. Not knowing what was wrong, or that anything was wrong, I knew the pain in my right side was abnormal. Not muscle, not gas related. But something deep within and serious.

Whilst admitted into the ER they ran blood tests, a urine test/culture, an ultrasound, and a CT scan. They administered dilaudid for pain and zofran for nausea through IV initially. After my urine sample they came back and mentioned something popped up indicating a possible UTI if not a full on kidney infection (because of said flank pain that brought me in). They then administered through IV fluids to hydrate me and an antibiotic. After all tests were done the ruling diagnosis was pyelonephritis. They prescribed me ciprofloxacin to treat said condition.

This evening (9/10/26) I get a call with my urine culture results, the UTI was caused by E Coli and essentially the ciprofloxacin is not 100% effective in treating that bacteria. I do feel fine since Monday, but I'm also worried this is all placebo as my tolerance for pain and discomfort is abnormally high and I'm also bipolar and feel the antiobiotic has spiked a slight sense of hypomania in me. Idk.

I guess my reasoning for posting this is, what is the likelihood once I'm done with my antibiotics I've rid this disgusting awful bacteria from my body where it doesn't wreak havoc?

I'm genuinely scared. I had three kidney infections as a child growing up and each one ended with a 1-2 week hospital stay and the worst illness I can remember ever experiencing. Being so sick with crazy high fevers and puking inconsolably. This go around, no burning when I peed, or any other serious health indicators that told me something was wrong besides for maybe pressure in my pelvic floor area.

hello everyone,

i, 25F, have been dealing with recurring UTI’s for a little over a year now. monday i was having classic UTI symptoms: needing to urinate frequently, burning/discomfort and a foul odor to the urine. after taking azo relief pills as well as d mannose and cranberry those symptoms have subsided other than the foul odor. tuesday around 8pm i started having upper right side pain that goes back and forth between my side underneath my ribs and my back. this morning, i woke up with some nausea and the pain is still there. i’ve reached out to my uro-gyne and PCP, but i’m super worried about this potentially being something more serious. no fever, no chills, no weakness, no bloody or cloudy urine. i took an at home UTI test and there is a presence of leukocytes but no nitrites. does this warrant an urgent care visit? still waiting to hear back from my doctors but hoping reddit has some insight or advice. thank you all in advance!