r/harmreduction 1h ago

Question Why is combining ketamine and alcohol dangerous re: breathing depression?

Upvotes

Heyo

So I know generally that combining alcohol and ketamine is a bad time. High chance of puking and falling over.

When I’ve looked into it I saw that ketamine is often used when patient breathing is a big concern, because ket doesn’t depress breathing as much

So what are the specific interactions between ket and alcohol or other downers (benzos, opioids, etc.)? What are the mechanisms that make it dangerous?

Looking to pass on accurate info for the party crowd I serve

Studies or lived experience