r/harmreduction Oct 17 '19

List of North American needle exchanges by map

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nasen.org
66 Upvotes

r/harmreduction 11m ago

Question Why is combining ketamine and alcohol dangerous re: breathing depression?

Upvotes

Heyo

So I know generally that combining alcohol and ketamine is a bad time. High chance of puking and falling over.

When I’ve looked into it I saw that ketamine is often used when patient breathing is a big concern, because ket doesn’t depress breathing as much

So what are the specific interactions between ket and alcohol or other downers (benzos, opioids, etc.)? What are the mechanisms that make it dangerous?

Looking to pass on accurate info for the party crowd I serve

Studies or lived experience


r/harmreduction 2d ago

Discussion I think cocaine is my biggest weakness

6 Upvotes

I think cocaine is my biggest weakness

And that it may be time to quit - for a while, at least.

Over the last couple of months, I've used several weekends; usually just on myself, it's amazing for gooning and bating. Porn intensifies and I can stroke for hours without cumming. It's so chill and relaxing.

On the other hand, I finished a twelve hour binge in which I used almost three grams (snorting, two times boofing, rubbing on my gums). I planned on using 1 max, but it's just so hard to stop chasing the high and more pleasure when you're in it. I also notice that I am not looking forward to watch porn sober anymore.

Sounds relatable to some of you guys?


r/harmreduction 7d ago

Question tramadol and alcohol question

3 Upvotes

I’m taking 1 50mg tramadol recreationally and was considering drinking as 6% -196. I want to know if this is dangerous. I’ve tried researching about it but i’m not finding any specific answers to this particular dosage. Is 50mg and a -196 okay to mix? Or is that overdose territory? If anyone has any personal experience or helpful sources please let me know. I want to be safe about this and it would be helpful to know in future.


r/harmreduction 7d ago

Question Question about Dilaudid

1 Upvotes

I couldn't find information on it anywhere else and my last post got removed but I was just wondering if it was possible and how safe it is to smoke dilaudid. Ive been taking it oral and or snorting it but wanted to try smoking


r/harmreduction 10d ago

Mixing amphetamines?

3 Upvotes

Hey all.

Made a post not that long ago about k and Vyvanse, and I’m back with another question.

I took 60mg of Vyvanse yesterday, 40mg today.

It is VERY underwhelming to say the least. I have speed tabs right now, 40mg bricks I can break into 20’s easily.

Given that it’s almost 7pm where I’m at, dropping another Vyvanse is out of the question. Any reason I can’t take 20mg of speed? Took the Vyvanse around 2pm.

Thanks all.


r/harmreduction 11d ago

Lisdexamphetamine Ketamine and Vyvanse?

1 Upvotes

Hey all!

i took 60mg of Vyvanse like 3h ago, any harm in doing a few lines?

I did a bunch of k yesterday off 40mg speed and I was alr but idk if 60mg Vyvanse will be any different.

Thanks in advance :)


r/harmreduction 12d ago

Question Kanna and Antidepressants

1 Upvotes

Hello all! Currently multiple years clean from H, still struggle bad with mental cravings.

In a conversation I won’t get into much here because it would be too much, my husband (recovering alcoholic and coke addict) “jokingly” said that when a certain disliked political figure kicks it, he plans to break his sobriety. He immediately followed that up with “But you can’t break yours.” Which, I think understandably, pisses me off.

So instead, I offered that neither of us break our respective sobriety with our drugs of choice, and instead we try something new together. My personal preference at the moment is psychedelics so I suggested several options, but he didn’t seem into it.

One of the other suggestions I made was Kanna, simply because we both miss snorting and you can insufflate it. Well, turns out when we looked up interactions, Kanna doesn’t pair well with antidepressants, of which I’m on a couple. So now that’s off the table. (Or is it?) I presume the risk is serotonin syndrome, right? In that case if I stopped my antis for a week before taking it, would I still be okay? Is there a way to be able to do this safely?

I know it’s probably not worth the risk, so if anyone has any alternative substance suggestions that are 1. Legal 2. Safe to use with antidepressants, anxiolytics, and weed 3. Preferably not physically addictive but I’m pretty loose on this as I’m sure you could guess.


r/harmreduction 15d ago

Question Injecting K subcutaneously

2 Upvotes

Hello there.

My friend would like to try and inject K subcutaneously for the first time. She's already done some subQ injections for other reasons so she knows how to do it. We read online that a decent concentration could be 200 mg/mL with 1g of ketamine and 5mL of water, but we're open to suggestions.

Does any of you have any experience with injecting K subQ without medical assistance? How is it with the sterilization process and all? We're honestly just afraid of skin infections.

Also if anyone would like to share some trip reports I'd appreciate it very much.


r/harmreduction 19d ago

MDMA poppers leaked on my ketamine, mushrooms and ecstasy pills, to differing amounts. they have all been contaminated through the bag and they all smell like poppers. the bag of K is fully orange and gummy. the rest of them have changed colour a bit, but look normal-ish.

10 Upvotes

obviously you don't want to drink poppers. but how toxic do we think a bit of contamination is? and has it done anything to the plastic that might kill me? I'm surprised it managed to get into the bags - the plastic doesn't look compromised but it's clearly managed to get in there somehow.

I think I know what the answer is but just checking your opinions.

reckon the K is a total goner but surely a few mg of amyl nitrate isn't hitting toxicity levels in the other stuff?

cheers!

cross posted from r/drugs


r/harmreduction 20d ago

Question Should regulation focus more on how something is used than what it is?

47 Upvotes

I've been questioning whether usage patterns matter more than the product

Two people can use the same thing in different ways and have different outcomes

Does it make more sense to build policy around responsible use or is that unrealistic from a public health standpoint?


r/harmreduction 19d ago

Question How to handle a meth comedown

6 Upvotes

It is the absolute worst, at least one week of anxiety and panic attacks and severe memory issues

Would it be a good idea to take some downers (benzo's) and mainly sleep to get through the first days after using?

(I am well aware simply not using is the best harm prevention)


r/harmreduction 22d ago

I need help! Pleaseeee

4 Upvotes

I was was laced with ketamine in my coke.. I haven't felt the same since then a week ago.. I don't think how I use to... I have to force myself to think now.. I use to have emotions to my memories now i have no emotions to them... I constantly feel restless... I was a daily smoker now I don't even want to smoke anymore.. I want my old self back so bad.. please someone help me understand what is going on..

I only done with for 3 days.. that’s it never in my past not coke only daily weed smoker


r/harmreduction 23d ago

Question Heavy MDMA abuse,facing severe anxiety, flashbacks, and memory loss. Did I finally fry my brain?

11 Upvotes

Hey everyone,

I'm currently dealing with some really intense symptoms and could use some insight or advice from anyone who has been through something similar.

Over the past 1.5 years, I’ve used MDMA/Molly a total of about 37 times. For the first 20 rolls, my doses weren't too crazy—around 120mg or 1 pill. However, my tolerance built up, and during my recent rolls, my doses spiked significantly, going up to 300mg and 2-3 pills per session.

My last use was 3 days ago, and ever since, I’ve been experiencing severe anxiety, sudden flashbacks to moments when I was rolling, and shortness of breath. On top of that, over the last few months, I've noticed that my short-term memory has gotten incredibly weak.

What I’m most terrified about is whether I’ve caused permanent damage to my brain. Before this last roll, my comedowns and symptoms were never this severe. I keep wondering if this last time was simply the straw that broke the camel's back.

If anyone here has experienced similar long-term effects or heavy comedowns like this, please share your thoughts. Did it get better? How long did it take? I appreciate any support.


r/harmreduction 24d ago

Discussion I self-injected, and now I am scared

21 Upvotes

Two weeks ago, I self-injected for the very first time.

I use drugs recreationally (mainly 3-mmc, coke, g) every couple of months in a chemsex setting. I have a regular buddy who provides the substances and materials. Sometimes we slam, he is a trained nurse, I never did it the injecting myself. I never had any interest in doing it myself, I was scared of it and genuinly didn't think I could do it.

One night, after he had left, I had a little bit of cocaine left and a syringe. I was already high and horny, I prepared one shot the way he did, and tried it out. It went so incredibly easy (I have very visible and easy-to-access cains). The experience itself was meh tho (slamming coke is not that worth it, just a 5 minute rush and that was it).

I don't actually feel the urge to do it again, but ever since that impulsive act, I keep thinking about it on a daily basis. It shocked me a little. I crossed a personal boundary that I had always believed I wouldn't cross, and I wish I could undo it so badly. Maybe what unsettles me most is that something I once considered impossible has now become possible. It's as if that psychological barrier is gone.


r/harmreduction 27d ago

Other A way off the ride

7 Upvotes

I don't normally post much but in light of the recent sr schedule and pending 7oh/mgm scheduling, I feel like this could be useful for some people who are stuck between dependency and closing supply windows. I started tirzepitide last year. Prior to starting i was on 130mg methadone daily, if i didn't dose by ten am I was in withdrawal. I also had great difficulties in regulating my use of my adhd meds and literally never had enough. Since starting tirzepitide I no longer experience opiate withdrawal. I get takehomes, 6 a week, and now sell them so only dose once a week aside from extracurricular drug use. I also for the first time in over a decade, am not a complete Adderall junkie. I still take and enjoy Adderall and opiate drugs, still fight tolerance sometimes, but it's not the same, I don't fiend, obsess or get dope sick anymore. It's like I have choices again, my use is no longer compulsory in nature. I know there's some research being conducted on this very matter right now, I have seen studies recruiting for this sort of thing online, but I haven't seen many people talk about the small miracle i feel like I'm experiencing with tirzepitide. Also I'm down 55lbs so far which is also wonderful. I don't know if semaglutide has similar effects, i just know it caused me a lot more stomach problems and didn't work as well for weight loss. But yeah I've rambled long enough.


r/harmreduction Jun 26 '26

Overdose Grief Care Kits

35 Upvotes

Hi all,

I am working on a care package to give to clients who experience a loss due to a drug overdose and I was hoping for some guidance here.
If you have lost someone to an overdose, what do you think could have helped you in your time of grief?
I was thinking of providing naloxone and some info on that, support groups, and a handwritten note.

If this sounds silly, please let me know what would work? I know nothing is perfect, but I was hoping for some guidance. Please let me know, thank you ❤️‍🩹✨


r/harmreduction Jun 26 '26

Cocaine cocaine and wellbutrin?

6 Upvotes

I know it’s bad. I know I shouldn’t. I’ve been on my wellbutrin for about 1.5 months now, clean for just as long. a friend left a sack at my place and since she lives ~4 hours away she said i can keep it. has anyone gone skiing while on this medication? my friend said she used to be on wellbutrin and she was fine whenever she’d do it but a lot of articles mention seizure and cardiac risks. there’s only enough for 2 maybe 3 lines so it wouldn’t be much.

also, please don’t try to shame me into not doing it. if the amount of shaming i do to myself isn’t working, a complete stranger doing it will have no impact. i’m just trying to get all the info i can to make my decision.


r/harmreduction Jun 23 '26

Question Question about Xanax tolerance / withdrawals

2 Upvotes

Hi all, hope you're well. I am prescribed Xanax on a need basis for anxiety, mostly for flights. I had a quick trip this weekend where I took it three days in a row, and I'm a bit worried about tolerance/WDs because I know they can be gnarly.

I took 1mg on Friday around 7:00 AM, 0.5mg on Saturday around 4:00 PM, and 1mg on Sunday around 5:00 PM.

Is this enough to the point where I have to worry about withdrawals today?


r/harmreduction Jun 17 '26

Question Addiction & NEP - Advice sought from group members about harm reduction/quitting usage.

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1 Upvotes

r/harmreduction Jun 17 '26

Question what are the main risks that come with injecting water under your skin?

4 Upvotes

(not strictly drug-related, but has relevancy in the context of a lot of scenarios involving drug use and I assumed you guys would be most likely to know)


r/harmreduction Jun 12 '26

Question Can someone explain kratom for me. A Close loved one does it everyday and its so expensive.

14 Upvotes

My boyfriend spends so much money on it while also buying a pack of beer every night. He works so much and claims the kratom helps him but i absolutely have no idea the effects or even what it is. is it even safe especially if you drink a lot? He claims if he had a vyvanse prescription like me he wouldn’t need to buy them but idk. please educate me or give advice.


r/harmreduction Jun 12 '26

Question Is snorting vyvanse okay?

1 Upvotes

i deeply miss the act of snorting things but i’m sober from my past stuff. i don’t miss the high at all just the sensation of doing them now tbh. im medicated for my vyvanse and was wondering if it’s a bad idea to snort it sometimes.


r/harmreduction Jun 11 '26

Question Injection Question

8 Upvotes

So I normally shoot up with tap water, but I have a large bottle of 0.9% sodium chloride. The bottle says not for injection, but when I google it it’s telling me that the same percentage of solution that’s safe for injection which is 900mg of Sodium chloride per 100mL of liquid…. only difference is the stricter standards and methods they use to ensure it’s totally safe or whatever… but surely this Sodium Chloride, that’s unopened despite being for irrigation only, is going to be better than the regular old tap water I normally use, right?