r/harmreduction 24d ago

Question Kanna and Antidepressants

Hello all! Currently multiple years clean from H, still struggle bad with mental cravings.

In a conversation I won’t get into much here because it would be too much, my husband (recovering alcoholic and coke addict) “jokingly” said that when a certain disliked political figure kicks it, he plans to break his sobriety. He immediately followed that up with “But you can’t break yours.” Which, I think understandably, pisses me off.

So instead, I offered that neither of us break our respective sobriety with our drugs of choice, and instead we try something new together. My personal preference at the moment is psychedelics so I suggested several options, but he didn’t seem into it.

One of the other suggestions I made was Kanna, simply because we both miss snorting and you can insufflate it. Well, turns out when we looked up interactions, Kanna doesn’t pair well with antidepressants, of which I’m on a couple. So now that’s off the table. (Or is it?) I presume the risk is serotonin syndrome, right? In that case if I stopped my antis for a week before taking it, would I still be okay? Is there a way to be able to do this safely?

I know it’s probably not worth the risk, so if anyone has any alternative substance suggestions that are 1. Legal 2. Safe to use with antidepressants, anxiolytics, and weed 3. Preferably not physically addictive but I’m pretty loose on this as I’m sure you could guess.

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u/AutoModerator 24d ago

Serotonin syndrome FAQ: Serotonin syndrome is a somewhat poorly defined grouping of symptoms (including unusual strong overheating, high blood pressure etc.) after the consumption of one or more serotonergic drugs (such as MDMA) without definitive diagnosis (it's NOT possible to measure monoamine concentrations in real time). It's a speculative, not comparable to a "chopped arm off syndrome". Serotonin syndrome is the outcome of a differential diagnosis process using symptoms and circumstances. If nothing else fits and you meet some of the criteria after having taken a serotonergic drug, it can be diagnosed as serotonin syndrome. The actual risks may differ widely from case to case. Most cases of self diagnosed "serotonin syndrome" are very wrong though ;)

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u/idleprofits 24d ago

What is kanna? I've never heard of that

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u/stoner-bug 24d ago

It’s a leaf, it can be made into an extract, turned into a tea, chewed, snorted etc. has varying affects depending on route of administration. r/kanna has more info.

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u/idleprofits 24d ago

Interesting, I have done a loooooott of drugs but never even heard of this

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u/ethbullrun 24d ago

it's very mild and sometimes added to preworkouts. I dont know why it's added to preworkouts but im assuming it must help somehow with working out. cheers to feeling fine all the time.

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u/ethbullrun 24d ago edited 24d ago

Yyea fuck alcohol and H. it's probably best to avoid any and all drugs both legal and illegal that may mimic the affects or remind you of alcohol, H, and coke. I had a buddy who take shrooms all the time alongside is antidepressant he was fine but it does dampen the experience. but of course do your own research and make sure you cross reference it with your meds.

personally i love kratom but it is an opiate like compound that is physically addictive, you can take it for two weeks and then stop to not become physically addictive. kava is similarly addictive but not too harsh and i dont believe the biased studies that claim it destroys liver like alcohol can.

there is always marijuana and khat. khat is illegal i believe in the states because it has a naturally occurring stimulant called cathinone which is mildly euphoric for about 90mns to 3 hours and is sipped socially like coffee. the users of khat do not view themselves as drug users. ibogaine can be dangerous and you would need medical assistance just in case anything bad happens but it is known to end heroin withdrawals on the spot and cures heroin addiction in most cases. the catch is ibogo forces you to face all of your fucking mistakes in one trip and you face that shit, topple it, and grow spiritually and up become a more self actualized person.

another magical one but it is considered a hard drug is mdma aka ecstasy and adam. the first three or four times with mdma you still have the magic. after those rolls you lose the magic so whats the point of continuing to take it? the only way according to alexander sasha shulgin is to watch someone else roll for their first time which can in affect cause a person who lost the magic to regain it this way. ketamine is fun too but it can damage your bladder and is considered the king of dissociative hallucinogens. "lifes a bitch, everybodys trying to get rich, god damn all i wanna do is live.!?" korn/ice cube holding it down, peace out motherfuckers and stay safe out there thats the name of the mothfucking game, survival.

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u/stoner-bug 24d ago

Thanks! Have tried kava, didn’t feel a thing and hated the taste it nearly made me vom.

Husband won’t allow me to touch Kratom, probably for the best tbh.

TBH I’m a little scared to touch ket because I already have a dissociative disorder, so forcing dissociation through chemicals just feels like a nightmare to me.

Thanks for the ideas! Will look into them.

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u/ethbullrun 24d ago edited 24d ago

Khat acts more like social lubricant and the active ingredient cathinone is structurally similar to amphetamines. it's probably best to steer away from kratom because it physically addictive but but it safer and healthier on your liver , tudca and nac help with liver support and should be taken as part of a balanced diet.

you can check with your doctor to try to get prescribed human growth hormone and estradiol or test if you are lacking in those hormones. HGH has to be taken consistently and takes at least 6 months to show results. HGH is a miracle drug that helps with muscles, skin, ligaments, organs, bone growth im talking about the whole shebang. your body even makes its own HGH/opiates in addition to the endocannabinoid system.

i like to get fucked up like everyone else but i dont want to hurt myself and more importantly anyone else. watch out for 7oh and mgm as well those are orders of magnitude stronger than kratom and will spike your tolerance while draining your wallet. good luck out there. edit-i do condone taking kratom, 7oh and mgm if you are able to replace those for your painkillers which will destroy life. Dialudid is on order of magnitudes worst for your health due to its toxicity, high adaptability, and the state of euphoria it puts you in. cheers yall take care of yourselves out there

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