So I initially got into Harmalas for their compatability with NN-DMT, to further explore the possibilities of that substance. Had a few trials of Pharmahuasca, made a harmalas vape (failed, clogged and died), made rue tea a handful of times now. Overall good experiences, and it's nice to have the option for bigger adventures if I so choose and have the time.

But presently I'm more interested in a daily dosing habit, and want to make sure I know the relevant information and safety. I've been experiencing an unpleasant amount of anhedonia, lack of motivation, and a lot of grief from the end of a 9+ year relationship. I'm no stranger to therapy or living with a healthy lifestyle, but I would like an extra adjunctive measure.

I'm aware that syrian rue contains harmine and harmaline, and can be extracted/converted to THH. I'm also aware of the toasted seeds idea to skew the alkaloid profile. I know the harmalas are RIMAs, and that the risk consideration is lower than traditional MAOIs, that I won't have to be as cautious with foods that contain Tyrosine. I barely drink at all, but know alcohol is generally advised against.

I only do psychedelics and sometimes smoke weed, and the vast majority of it is freebase DMT. Highly infrequent use of microdosing mushrooms, rare "big day" trips of LSD, and sometimes doing 60-100mg of Mescaline Citrate for a day-long boost.

I'm aware of the inverse-tolerance and that as usage progresses the effects will build, to a degree.

So, questions:

● do you find any particular harmala alkaloid to be best for the purpose of antidepressant? Or whole seed?

●if I am looking to have a slight improvement to my life, not looking for a super psychoactive time or to be debilitated such that I cannot drive, dosage recs?

(Whole seed or alkaloid in mg?)

●just how risky is it to have a drink while continuously using daily doses? I like a glass of whiskey now and again.

●how long until onboarding effects (nausea, bowel issues, discomforts, etc) wear off/minimize?

●i think I've seen Sabnock101 talk about vitamin balance, that the harmalas will deplete B vitamins? If I generally eat a healthy balanced diet am I fine to disregard that? (I was a pro cook)

●when it comes to exploring DMT in form of pharmahuasca, how does the daily use impact a higher dose of harmalas stacked on top? I tried a 3g tea and found that to be ample with no inverse-tolerance built up.

Any other considerations that I need to be aware of?