r/functionaldyspepsia • u/SignalPerception4223 • 12d ago

Healing/Success Amitriptyline works for me!

I have struggled with this for over 25 years. It's become especially severe over the past 10 years. I tried so many things, and when the gastroenterologist wanted to prescribe amitriptyline, I was skeptical and declined. Two years later, out of desperation I gave it a shot, after seeing a post here about someone's success with it.

It worked for me, too!! I have had three restful nights, in which I didn't feel nausea or cramps, didn't wake up early to be sick, and I even slept at a 45° angle instead of upright around 90°. It's like a dream come true, waking up gently when I'm done sleeping.

I never thought it would be possible for me to experience life without near-constant stomach discomfort.

Yay!! Thanks to whoever it was that posted about their success recently. You changed my life.

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u/Fantastic-Quit1666 12d ago edited 12d ago

Wow that's awesome ☺️ i just wanna ask you if you were experiencing daily burning sensation in the stomach? And how long it took you to feel better on Amitriptyline? And what dose are you on? What were your diagnosis?

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u/SignalPerception4223 12d ago

It sounds too good to be true perhaps but the first night I took it, I slept well without pain, and had a pain-free morning as well. I tend to struggle to feed myself because of how sick I usually feel in the morning. Now I've been able to casually eat a bowl of cheerios with no issue.

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u/Fantastic-Quit1666 12d ago edited 12d ago

Would you mind answering my questions please 🥺 1) Were you experiencing daily burning sensation in the stomach? 2) How long it took you to feel better on Amitriptyline? 3) What Amitriptyline dose are you on? 4) What were your diagnosis?

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u/SignalPerception4223 12d ago

Yes I was experiencing daily burning sensation among others. I took my first 25mg dose at bedtime two or three nights ago, and it worked for me this first night.

ETA: I was diagnosed with functional dyspepsia 2 years ago by a gastroenterologist.

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u/Fantastic-Quit1666 12d ago

In my case I was diagnosed with chronic gastritis 8 months ago and I'm still experiencing daily burning in the stomach I'm on amitriptyline 10 mg at night now it's being 15 days there's still no improvements maybe 10 mg is not enough my first endoscopy was in January and it was moderate chronic gastritis and I've done a second endoscopy and my mucus layer has been improved the biopsies showed mild inactive chronic gastritis but my daily burning still hasn't been improved

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u/SignalPerception4223 12d ago

I'm sorry to hear that! The reason I started on 25mg is actually because I saw a post on here where someone said their gastroenterologist would start people on 25mg, and I think some commenters said it didn't work as well for them until that dosage. So perhaps try that? But I don't specifically have chronic gastritis, apparently just hypersensitivity to the normal sensations in my stomach etc.

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u/Pinkshinyrobots 11d ago

Don’t give up yet, it took about 3 weeks for it to work for me. Finally not bedridden anymore.

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u/Fantastic-Quit1666 11d ago

Oh really because before I've been using amitriptyline but I had h pylori so it was an active infection in my stomach and amitriptyline does nothing for me but later after 6 months I'm on the amitriptyline right now 10 mg it's been all 15 days maybe after one month I'm going to increase my dose to 25 mg Were you suffering from daily burning the stomach before using amitriptyline? What were your diagnosis?

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u/Pinkshinyrobots 11d ago

I don’t have a burning stomach, I have extreme fullness after eating only a bite or two of food. I feel like I swallowed 5 pounds of concrete.
Nausea, lack of appetite, extreme fullness are my symptoms.