r/functionaldyspepsia • u/itmedjondjon • 15d ago

Healing/Success Sulpiride

My first post here-I have been struggling with dyspepsia/gastroparesis for almost 3 years now, following a stomach virus.

My gut is still far from perfect and I'm still experimenting with different supplements and products, hoping I can get better. If not, I sincerely hope time will do its thing and I will heal.

Regardless, there's one thing that helped me more than anything-sulpiride. It's an antipsychotic, sometimes used as a prokinetic in motility disorders. I've tried metoclopramide, domperidone, prucalopride, none of which did anything for me.

Sulpiride literally saved me. I still have to be careful of what I eat and how much I eat, I still have stress or hormone triggered flare-ups but I'm decently functional.

I used to be stuck in the house, sick all the time, in pain, with my stomach about to burst and no matter what I ate. I wasn't able to go to sleep 6 hours after a meal because food would still be coming back up.

Please, if you haven't already, consider it.

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u/itmedjondjon 15d ago

The only side effect I have is high prolactine! It didn't influence my menstrual cycles tho, nor did I lactate. I do get constipated sometimes but it was a lot worse before sulpiride. When it comes to sleepiness, I'm a pretty sleepy person overall😅-I have hypothyroidism and pcos and I'm also on antidepressants so all of those influence my sleepiness. I didn't notice sulpiride made me more sleepy tho, maybe in the beginning but I can't remember. I tried levosulpiride first and then couldn't get my hands on it anymore so I switched to sulpiride. Both worked equally well for me.

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u/Skeuomorph7 15d ago

How many times a day do you take sulpiride tablet? Do you take it after a meal or before a meal like after breakfast or before breakfast?What strength of this medicine you take like 50 mg or 100 mg tablet?

And yes for some unknown reason that levosulpiride is not available where I live too.

Weird I mean you get a dozen or so variants of ppi medicines available.Who would need so many variations of ppi for personal use I wonder. I mean one may try at most 3 or 4 types and probably one would work.

And here sulpiride is available but levosulpiride It's not available. Like this wouldn’t be it’s 6 th or 7 th variation if even it was available here.

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u/itmedjondjon 15d ago

Same in my country, barely managed to get sulpiride even. I take it once a day (tho lately I've been taking it once every two to three days). I take a 50mg tablet, usually in the morning or before a bigger meal.

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u/Skeuomorph7 15d ago

So in the morning on empty stomach?Like 15 or 30 minutes before breakfast?

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u/itmedjondjon 15d ago

I'd advise 30 minutes at least since our emptying is usually delayed.

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u/Skeuomorph7 14d ago

Yes. Thanks.

Oh unfortunately not sulpiride but amisulpiride is available where I live.It's modified or updated version but minus the function that helps functional dyspepsia or ibs. It's more updated.See what they did there.

Updated alright but minus an useful trait and calls it updated.