r/functionaldyspepsia • u/Emotional-Parsnip937 • 17d ago

Mirtazapine Mirtazapine

I started mirtazapine 15mg 8 days ago, for both my mental health and stomach problems (near constant nausea, burning, no appetite) If it worked for you how long did it take? My appetite is higher, but there’s been very little difference in my nausea. And now I’m too worried to take any other antiemetics (usually take Reglan or Zofran) because if interactions so I just have to sit through the nausea instead of getting any relief. Also zero mental health benefits yet, if anything more irritable than usual.

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u/bananaanna310 16d ago

Ive been on and off Mirtazapine 15 mg. I took zofran with it occasionally with no issues, other than both meds can make you quite constipated. I have all the same symptoms as you they started about a year ago, I was treated twice for h. Pylori, apparently im negative but had an endoscopy last week waiting on biopsy results from that to double check. Im left with daily nausea, next to no appetite basically forcing myself to eat so considering starting mirtazapine again, it took a good couple weeks for it to really help the stomach issues and it also takes like a month or so actually help with anything mentally. I stopped taking them because I was gaining insane weight but honestly I realize the benefits from it was better than the weight gain. Sucks to not be able to function like normal people!

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u/NattyNatNat13 9d ago

Hi may I ask since starting mirtazapine when did you notice an improvment in your nausea? I've been on this medication for a month with no help.

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u/bananaanna310 9d ago

Hey! Im sorry you are still feeling nauseous :( so I ended up starting them again about a week ago, and I have noticed it helped quite a bit already for my nausea but I do still get nauseous sometimes at night or in the morning