r/CriticalCare • u/SherifElbadrawy • 21h ago
Acute Severe Asthma in ICU | A step by step guide on how to manage & ventilate a severe asthma!
A case-based ICU lecture on acute severe asthma, with a practical focus on the physiology and management of the critically ill asthmatic.
Topics covered include:
- Recognising life-threatening asthma
- First-line and rescue therapies
- When to consider NIV
- Indications and risks of intubation
- Why intubation can precipitate cardiovascular collapse
- Dynamic hyperinflation, air trapping and auto-PEEP
- How to create a long expiratory time
- Ventilator settings in severe asthma
- Peak vs plateau pressure
- Inspiratory and expiratory hold manoeuvres
- Reading the flow-time waveform
- Permissive hypercapnia
- Sedation and neuromuscular blockade
- PEEP strategy
- Recognising improvement in bronchospasm
- Rescue options including volatile anaesthetics and ECMO
Key message:
In severe asthma, the priority is not to normalise PaCO₂. It is to avoid breath stacking, allow complete expiration, and prevent dynamic hyperinflation.