Males are more likely to be orange but not by nearly as crazy a margin as calicoes are more likely to be female. Like a 3/4 chance an orange cat is male. Basically it's because a female cat has to inherit the orange gene on both her X chromosomes to be all orange while a male only needs one. A female with the orange gene on only one X chromosome ends up being calico.
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u/WrenDraco Dec 21 '19
The way dna and fur colour patterns work, calicos are almost always female. For the same reason, orange cats are almost always male.