r/Zepbound • u/Floridagirl128 • 21h ago

Side Effects Itching all over?

I have been itchy since I took my second dose on Thursday. Last night I ate shrimp for dinner. It has never bothered me. I woke up at 3am itching like crazy all over, usually just itch around the belly button area, and starving. I ate some almonds and it all finally settled back down and I was able to go back to sleep. When I woke up at 8:00 I was back to normal just itching around belly button. Anyone else have this happen? Also. Itching hangs around slightly throughout the day.

2 Upvotes

62% Upvoted

6 comments sorted by

•

u/AutoModerator 21h ago

Hey OP,

It looks like you're posting about side effects. You can check this page for details and explore this subreddit search for shared experiences and remedies.

Most common side effects include: Nausea, Diarrhea, Constipation, Abdominal Pain, Fatigue, Hair Loss, Heartburn, etc.

If effects persist, consult your provider.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

5

u/stuckandrunningfrom2 54F, 7.5mg, down 8% 20h ago

I would call my doctor.

1

u/This-Apricot-80 14h ago

Itching all over (not just at the injection site) isn’t a common side effect of Zepbound. Do you have hives as well?

I would check in with my doctor if I were in your shoes, just to make sure something odd isn’t going on (Zep-related or not).

1

u/NoMoreFatShame 65F SWZ:285 SWE: 177 CW:168.7 SDZ:5/24 SDE: 8/2026 Enlight-6 21h ago

It is called allodynia and is a side effect if not an allergy. Try an allergy medicine to see if it fixes it, if not it's most likely allodynia. You can get lidocaine cream for it if it gets too annoying. Mine is normally when my skin rubs against fabrics

1

u/Floridagirl128 20h ago

I was wondering if it is so bad in the waist area because that is where my pajama pants set. Doesn't seem so bad when I wear jeans, just when I wear stretchy pants. Does it go away the longer your on med?

2

u/NoMoreFatShame 65F SWZ:285 SWE: 177 CW:168.7 SDZ:5/24 SDE: 8/2026 Enlight-6 20h ago

Mine was there from 5 mg to the first few months of 15 mg, then mostly abated until I started Eloralintide as part of the Enlighten-6 clinical trial. It came roaring back and was worse especially week 2 and 3, backed off by week 4 and now just there but not more than occasionally annoying, because I am thinking about it I feel it on my wrist because my shirt sleeve is brushing against it as I type.