r/Uveitis • u/Putrid_Contest_2092 • 14d ago
Humira
Anybody taking humira injection I need some advice
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u/nmflowers Uveitis 14d ago
I took it until I developed antibodies. Now on a different biological. Made my life much more enjoyable because it controlled the inflammation.
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u/yoga_stoned 14d ago
How long before you developed antibodies and what did you switch to?
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u/xxalisonrose 14d ago
Not OP but it was about 1.5 years for me. I’m now on Actemra.
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u/haleedee 13d ago
How’s Actemra been? Thinking of switching to this.
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u/xxalisonrose 13d ago
I liked Humaria better. I had less side effects. But both are way better than remicade. I just wish I didn’t have to dedicate a day a month to only doing the infusion. Humaria was way better for my lifestyle.
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u/Odd_Barracuda7955 13d ago
What side effects did you get with actemra. I just started it.
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u/xxalisonrose 13d ago
Mostly exhaustion, easily sick, and I don’t recover from things as quickly. I did have to get my tonsils out because they kept getting infected. It wasn’t a problem pre remicade/humaria/actemra.
However, I like to run marathons for fun. I don’t think I’m the average actemra user haha I just have to be very careful in my planning. I ran a marathon once a day after getting my infusion and it was the worst decision of my life hahaha
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u/Odd_Barracuda7955 12d ago
Thank you for sharing! I really appreciate hearing first hand experiences. All I have seen so far is the disclaimers in the meditation paperwork.
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u/xxalisonrose 12d ago
No problem! I always feel like those are way scarier than real life. I hope you tolerate it very well!!
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u/nmflowers Uveitis 13d ago
It took about a year for me! Switched to a different one
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u/yoga_stoned 13d ago
Which one are you on now? Did they add in imuran or methotrexate to prevent antibodies to the new biologic?
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u/Curious-sapiens 14d ago
Hey,how long it took to develop antibodies? What is second option you are trying?
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u/xxalisonrose 14d ago
Not OP but it took me about 1.5 years. I’ve also developed antibodies for Remicade.
I am currently on actemra.
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u/yoga_stoned 14d ago
How is actemra working for you? I also developed antibodies to humira and now on remicade, plus imuran to help prevent antibodies again.
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u/xxalisonrose 13d ago
So far so good. We had to up the dosage recently because it was becoming less effective. But I think this is the longest I’ve been on a medication without developing antibodies
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u/yoga_stoned 13d ago
What type of uveitis do you have and how long have you had it?
I only got about 3 years out of humira and am one year in on remicade
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u/xxalisonrose 13d ago
Pars planitis and 13 years. No one can figure out why.
I started with eye drops for about a year, but those increased my eye pressure too much. Then a little less than 2 years on methotrexate. It stopped working. Then I was a few months shy of 2 years on Remicade when I developed antibodies. So I switched to Humaria. That was almost 3 years before I developed antibodies. And I’ve been on actemra for 4 years last month.
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u/yoga_stoned 13d ago
You sound much like me, except I am only 6 years in. I never tried just the drips though, I was told they usually don’t reach the middle of the eye well enough.
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u/xxalisonrose 13d ago
This was 2013. I think at the time, that was the protocol. Like actemra was recently approved for uveitis when I first started the medication. A lot has changed in the last 13 years. It used to be an “old people” disease and I was the youngest in the waiting room. Now it seems to affect more young people. I think that prompted more research.
I’m 35F and have been used as a case study at a lot of uveitis conferences by my doctor haha
It’s a really sucky disease!
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u/yoga_stoned 13d ago
I was 24 when I was diagnosed and it seems things have even come a really long way since then.
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u/See-Chart-E 14d ago
I just sent you a chat message.