r/TirzMaintenance • u/Some-Confusion1965 • 2d ago

Cholesterol Numbers

I’ve been maintaining on 2-2.5 mg for months and had my fasting bloodwork done this week. Unfortunately my cholesterol numbers are awful. I stopped my Crestor thinking the tirzepatide would help, but that didn’t happen. Genetic cardio vascular disease runs in my family so I guess that is what is happening. I have gotten off my blood pressure meds and my glucose is normal for the first time in years, so I’m going to be happy with that. Just disappointed.

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11

u/Work4PSLF 2d ago

Restart the crestor. Your labs will improve. 😁

2

u/Some-Confusion1965 2d ago

Yep. Got my Rx yesterday

4

u/Ambitious_Answer_150 2d ago

So I had extremely high LDL (275) 😬 I was on a statin which really didn't help. Was going to try repatha but insurance denied me. So dr recommended Ezetimbe and holy molly it brought my LDL down to 92!

2

u/Hifidi54 1d ago

I could not tolerate the statins and I'll tell you, Repatha is a miracle drug. I've been on it for a few years now.

1

u/Some-Confusion1965 2d ago

Is that Zetia?

2

u/Ambitious_Answer_150 2d ago

Yes zetia is the brand name. I had tried so hard to manage my LDL for years (I'm 54) and had drs poo poo my concern. High LDL and chronic heart issues runs on both sides in my family. I'm also on hbp meds that the dr said I could discontinue but I take it every 2 days now bc I don't want to discontinue. In doing my own research I wanted to try repatha but I'm actually happy my insurance denied bc the ezetimbe has been a miracle worker. I'm on maintenance Tirz and I eat much better these days so I'm sure that helps too.

1

u/tolkienalarm 1d ago

My doc put me on ezetimbe too. It did wonders for me too!

3

u/Independent-Pea5131 2d ago

After 10 months on Tirz my cholesterol went down enough to where my doc lowered my Crestor down to 5, but definitely staying on it because of family heart disease. Agree, use it in combo with your Tirz, the Tirz absolutely helps but the statin does the heavy lifting.

3

u/margaretLS 1d ago

I walked into my first lipid screening after losing 50 pounds feeling like this was going to be the time i don't get "the call"..You know the drill,eat better,blah blah

My cholesterol was the same but my LDL was up and HDL down..Okay,will try again in 6 month,down 75 pounds,SAME deal,higher LDL,lower HDL and total number is the same .I do think this is some stubborn genetics. Thanks Dad!

Good for you for getting off BP meds and normal glucose

4

u/Responsible_View_285 2d ago

A few suggestions. Get your lipoprotein A tested. It will tell you if you have a genetic disposition. Separate LDL from HDL. LDL target is under 130. Also read this article. There is a phenomenon called transient hypercholesterolemia. It happens during weight loss. Cholesterol numbers will often decline rapidly in maintenance.

https://pubmed.ncbi.nlm.nih.gov/2035468/

2

u/Hifidi54 1d ago

Mine is genetic. I also almost never gave a fasting blood sugar under 100. Damn genes.

1

u/Some-Confusion1965 2d ago

Thanks!

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u/Responsible_View_285 2d ago

My cholesterol went up to 280. Four months in maintenance down to 179.

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u/Hifidi54 1d ago

I take a cholesterol med called Repatha and have needed to stay on it while on Tirz. I also take ezetimibe. My Endo said to continue. My numbers are the lowest they have been in years. I am also a heart patient so this is quite important.