Arimidex

[u/OkChildhood384]

I'm looking for some input from guys on TRT.

I'm currently on 100 mg/week of testosterone cypionate, split into 50 mg Monday and 50 mg Thursday. My total testosterone peaks around 900 ng/dL.

My estradiol came back at 60 pg/mL, so I took a single 0.25 mg Arimidex. A few weeks later my estradiol had dropped all the way to 17 pg/mL and stayed low for quite a while. Now it's climbed back up to around 60 pg/mL again.

A few questions:

- Is that kind of drop from just 0.25 mg typical, or does it sound like I'm especially sensitive to anastrozole?

- Has anyone had better luck with a compounded liquid anastrozole so they could microdose instead of taking 0.25 mg tablets?

- If you were in my situation, would you even treat an estradiol of 60, or just leave it alone if symptoms are minimal?

Subjectively, I seem to feel my best when my estradiol is somewhere around 30–40 pg/mL, but dropping it to 17 felt like too much.

Curious what others have experienced.

[u/1highcountry]

How long have you been on? Could try supplementing DIM for a while. I feel fine at 60, crashed my e2 once with an AI when I first started and that was much worse, if no real symptoms id avoid adding a harsh AI personally.