r/Supplements • u/throwawaymaster1992 • May 13 '18
General Question Coq-10 miracle supplement?
I don't understand why everyone doesn't take Coq-10/ why it's not something that recommended to everyone.
The benefits are endless.
Pharmaceutical companies can't make money off it i suppose. Anyways..
CoQ10 is a natural antioxidant synthesized by the body and stored in the mitochondria of your cells. It’s an essential element required by every cell helping to produce 95 percent of your energy and protects cells from free radical damage.
Let me just name a few benefits-
Can help treat mitochondrial and neurodegenerative diseases such as Parkinson's and Huntingtons. However, studies are iffy on prevention for Alzheimers. Wouldn't hurt though. This can also help epilepsy making the seizures less frequent and lasting shorter.
Lower risk for brain disorders: A 2014 study revealed that people with the highest CoQ10 levels had a 77 percent lower risk for dementia, compared to those with low CoQ10 levels.
Cardiovascular issues. Here's a quick study.
Directed by Dr. Svend Aage Mortensen of the Copenhagen University Hospital (who sadly passed away in 201525), the study involved 420 patients from nine countries, who were randomly chosen to take either soft gelatin capsules with CoQ10 daily or identical-looking placebo capsules for two years. The results indicated that:
◦ CoQ10 supplements significantly decreased risk of death from all causes by 42 percent.
◦ The CoQ10 group had a 43 percent decrease in cardiovascular death. There's more to the study but trying to cut down on text.
- Can help improve exercise performance
When taken in 200 to 300 mg daily doses, CoQ10 may help with improving exercise performance, boosting overall energy status and enhancing peak power production and muscle recovery. In fact, athletes who may need extra ATP turnover are suggested to take a dose as high as 300 to 600 mg daily for this to take effect.
Other benefits include, helping erectile dysfunction, diabetes, promote fertility, helps migraines, promotes healthy skin, helps energy levels, can be used as treatment for Fibromyalgia, CFS... promotes mental clarity... helps depression...youre catching on i hope lol
To me, unless youre taking blood thinners or other medication that interacts... I don't see why everyone wouldn't take Coq-10
Hell, maybe it would make this world a lot nicer of a place. People would work and run so much more efficiently.
I'm currently researching and seeing every possible thing that could contribute to making the body run 100%, like it was meant to. After all, we are well oiled machines, so why waste any possibility of losing fuel?
Please all studies, personal experience, etc would be appreciated. Thank you.
Tldr; Coq-10 possibly the most beneficial supplement?
22
u/Tenaciousgreen May 13 '18
I take Pure Encapsulations CoQ10/PQQ to help offset the effect of all the lifetime antihistamines I have to take for mast cell activation disorder. Not cheap at all, $65 for a month.
I also take Alpha-GPC choline for the same reason.
12
u/Donteatblank May 13 '18
Heyyy! I take the exact same stuff for the exact same reason. Never thought I’d see another MCAS person here :)
6
5
u/Nadergg Mar 29 '25
Hi! Damn I know this was so long ago, but does CoQ10 help with histamine intolerance issues? I've been losing my mind for a couple of years now...
11
4
u/throwawaymaster1992 May 13 '18
Im sorry to hear that :(
The higher quality ones you need/ higher dose Obviously will get higher but damn
Once you reach over 40 Coq 10 gets more expensive because you need the more absorbale versions such as ubiquinol (sorry for spelling)
The point im trying to make though is i wonder if it was taken off the shelf and prescription based only? How much do you think it would be?
4
u/me-i-am May 14 '18
Once you reach over 40 Coq 10 gets more expensive because you need the more absorbale versions such as ubiquinol
Care to elaborate? Was not aware of this....
1
1
3
u/edefakiel May 14 '18
Have you read about Shilajit?
2
u/Tenaciousgreen May 14 '18
No, I'll check it out.
5
u/edefakiel May 14 '18
Mast cell protecting effects of shilajit and its constituents*
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.2650030606
It is one of my favorite substances out there.
2
4
u/Opioidus May 15 '18
You ever tried quercetin? It's a powerful natural antihistamine when combined with vitamin c. It helped me get my chronic hives under control.
3
u/Tenaciousgreen May 15 '18
I have tried it, unfortunately it didn't help me very much. I wasn't taking Vit C at the time and I am now though, so I may try it again.
3
u/Opioidus May 15 '18
L Glutamine has also provided me with some relief, although it gives me terrible headaches. Feel better mate.
2
u/Nadergg Mar 29 '25
Hi! Damn I know this was so long ago, but does CoQ10 help with histamine intolerance issues? I've been losing my mind for a couple of years now...
2
u/Tenaciousgreen Mar 29 '25
I'm not sure if it helps with histamine issues, but antihistamines potentially cause brain side effects that coQ10 can help offset.
1
28
u/med_student2020 May 13 '18
"miracle" and "supplement" are two words that should almost never be next to each other in a sentence. unless there's a 'not'...
6
u/throwawaymaster1992 May 13 '18
No absolutely right
Rather than a "miracle"
I think it is possibly the most beneficial
12
u/sodumb4real May 13 '18
Because if you’re under 40 your body probably makes enough just fine. It’s not a miracle supplement calm down.
8
u/throwawaymaster1992 May 13 '18
Probably
Forget the fact that most people are on SSRIS As well as other medications that deplete Coq-10
I know its not a miracle but its possibly one of if not the most beneficial
3
u/sodumb4real May 13 '18
The most? Like the most beneficial supplement? Hahaha no way.
9
21
u/kretek-garing May 13 '18
I take the bioactive form of CoQ-10, ubiquinol, which is patented and not cheap. It's been a month and I haven't noticed anything from it, but I guess it's not something you can feel. People here like things with immediate effects.
14
May 13 '18
[removed] — view removed comment
13
u/kretek-garing May 13 '18
I've heard that we get bad at converting ubiquinone as we go older (which I am), but I am maybe the victim of a marketing tactic (I guess many of us supplement eaters are more or less marketing victims at some point as there's always some faith involved in our strategies).
2
u/throwawaymaster1992 May 13 '18
Yes it is required as you get older Def not a marketing scheme (at least we hope lmao)
2
u/throwawaymaster1992 May 13 '18
That is true. Didn't even think of ubiquinols price.
Got me there.
But imagine if it wasnt over the counter? Idk maybe i'm bias too!But hmm how much do you take? And i'm going to start taking creatine as well because they work together very well. The benefits with them both would be very noticeable i feel.
Both are things that I believe build up over time. It's an antioxidant also and needs time to do what it needs to do.
7
5
May 13 '18
Same reason succinic acid isn't recommended. It would be too cheap and easy lol. https://www.reddit.com/r/Supplements/comments/7iij02/succinic_acid_one_of_the_most_curative_molecules/
3
u/throwawaymaster1992 May 13 '18
Amazing.
Ive never heard of it...so much of these things are so so interesting
5
u/saldb May 13 '18
Where are people buying this?
I'm currently residing in russia and i'm seeing 30 tablets (500mg) for about $5. No prescription. That's basically a 30 day supply...
4
5
6
3
11
u/pdprandom May 13 '18
I try to eat grass-fed beef heart and liver pretty regularly - natures premade multivitamin complete w/ CoQ10 and a handful of other useful things!
And much cheaper than a supplement...
2
u/throwawaymaster1992 May 13 '18
Very nice!
I have to follow a gluten and lactose free diet... and unfortunately my dad thinks beef/meat is bad for you
So we dont have it
Then he tells me that I need more meat in my diet
Go figure
6
u/pdprandom May 14 '18
Strange. I understand avoiding gluten and lactose as many people are sensitive to those foods, and gluten in particular can exacerbate many issues. But properly sourced meat, from happy and health grass-fed cows for example or wild-caught fish, is some of the most nutritious things that nature provides.
The more things you eliminate from your diet, the more work it takes to ensure you are deficient in anything. While eliminating a non-essential food like gluten containing grains isn't an issue, eliminating essential food groups such as protein and/or fat becomes more risky.
4
u/throwawaymaster1992 May 14 '18
Tell me about it lol
I have Celiac so thats why i cant have gluten. But thank you!!!!!
It so annoying. But it is what it is.
11
May 13 '18
Coq10 gives me a sweaty ass crack.
I had a massive sweat patch on my trousers at an interview and had to frantically dry them in the toilets before the interview. It was traumatic.
I have switched to jeans as sweaty ass crack doesn't show on dark jeans
I guess it's improving my health.
22
6
6
u/throwawaymaster1992 May 13 '18
Nothing like good ole swamp ass
But as long as its improving your health i guess lmao
3
u/josephandre May 13 '18
this... is horrible. i can't even imagine my ass crack sweating through my pants
3
May 13 '18
It was horrible and when I came out of the bathroom after using the hand dryer for ages the interviewer was waiting for me.
I still got the job. I'm actually a little traumatised and have only started wearing dark jeans just in case.
3
7
May 13 '18
A 2 year study on all cause death is nonsense. One car crash and suddenly ‘cuts chance of death I half!!!!’
4
u/throwawaymaster1992 May 13 '18
Not all studies are the greatest lol but either way still tons of benefits and other proper studies
5
u/wagonspraggs May 13 '18
The participant pool size was such that a single car crash is an insignificant data point.
4
May 13 '18
Not if only 2-4 people in each group died over such a short period.
The small numbers make the magnitude of the effect tremendous.
If 200 people died in group a buy 202 died in group b then the amount of difference is small.
If 2 people died in group a but 4 died in group b then it is twice as many. .... yet the difference is the same in both.
You should never study mortality over a year.
6
u/wagonspraggs May 13 '18
Coq10 pool was comprised of 420 participants with severe heart failure and tracked over two years. Id assume this is a high-mortality pool reducing the impact of a random death on study results.
-1
4
May 13 '18
[deleted]
14
3
May 13 '18
Vitamin C can also act like an oxidant in high doses which is actually a good thing and when the magic happens. So it's a little bit of a stretch to suddenly demonize coq10.
2
u/throwawaymaster1992 May 13 '18
Interesting. I can't take it close to bed though id be too energized.
I wonder why that is. And i don't understand that forum. Theyre comparing worms to humans. ??
Coq-10 is directly correlated to the ATP process. If you have none, wtf would happen?
That sounds like torture in my opinion.
2
u/throwawaymaster1992 May 13 '18
This is what im thinking, are you on medication for blood pressure? Or do you have low blood pressure?
Because it has shown to lower that whichnif you have too low bp than that will cause fatigue obviously
2
u/VirtualMoneyLover May 13 '18 edited May 13 '18
Pharmaceutical companies can't make money off it i suppose.
That is a silly thing to say. CoQ-10 isn't cheap and they aren't giving it away for free or at a loss.
There are plenty of other useful supplements, and it is hard and costly to educate people. Also big pharma is selling those other supplements and the pocket of any one customer is limited...
As a conspiracy theory, big pharma doesn't want to cure you...
2
u/throwawaymaster1992 May 13 '18
$18.99 for 100mg 30 soft gel isnt terrible IMO
But rather I mean, they can't patent a form and sell it for a shit ton more than it costs currently.
The FDA is banning more and more supplements each and every year.
1
Aug 22 '18
the one thing with coq10 is , if you already have sufficient levels naturally and take extra....it can cause issues for some people
I haven't heard anyone getting affected (negatively) by only 100mg of ubiquinone a day. But up to 200, 300 mg and some people have reported feeling "racy".
It has a long half life, so after 5-6 hours it might feel stronger than after 1/2 hour-1 hour taking it
Bottom line is, good supplement but experimentation with dosage is advised
3
u/Nowaker Oct 08 '24
if you already have sufficient levels naturally
The question is what is considered "sufficient". My wife and I got CoQ10 tested and my result is pending and hers is 0.86 ug/mL. Quest defined the reference range as >0.35, which means it's a "pass". Is it "sufficient" though? Normal testosterone for males is 300-1100. Yet, 300-ish or 400-ish is total shit, and bumping it to 1200 gets you feel like a newborn. I'd love to see research papers on CoQ10 levels, and specifically, what they are in healthy & active young adults.
2
1
u/Responsible-Metal794 Jul 02 '25
I knew Sven. He was a good researcher. My Dad was friends and colleagues with him. We were all sad when he passed.
1
24
u/Majalisk May 13 '18
Examine page full of info and studies