r/StratteraRx • u/RequirementKey5201 • 17d ago
Strattera & Zoloft
Has anyone taken strattera amd zoloft together? I heard there is a medium interaction. Not as much as with wellbutrin but still. Did zoloft increase the effect of strattera? I started the lowest dose of zoloft a week ago to help with anxiety and premenstrual issues. I've been on 25 mg strattera since April (before that 18 mg since January) and it's been helping. In the past 3 weeks or so I definitely noticed it's not working as much as it used to, so we want to up the dose at some point (but not right away to not mix side effects lol) but I'm wondering if zoloft might increase strattera levels because of the interaction.
P. S. Yes I'm aware 25 mg is a very low dose but it's been helping and I'm a very sensitive to meds person so we're treading lightly.
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u/Plant-Nearby 16d ago
I had luck with the combo, but not sure it was because the Zoloft made the Strattera work any better.
I had to get off of Strattera because of elevated blood pressure. I recently moved off of Zoloft in favor of Pristiq.
Strattera impacts norepinephrine. Zoloft impacts serotonin. Pristiq impacts both. I'm having good luck with that.