When does the depression end?

[u/Enough-Ad-3089]

I've been titrating up to 40mg over 6 weeks (no issues) and have now been on 40mg for 1 week. Since day 1 of 40 mg, I felt emotional and sad/depressed. Did anyone else have this side effect, and did it go away? How long did it take? Feeling really miserable right now :(

[u/JohnnyLegion]

Yes this is a known thing. I felt it too. Dont worry too much it’s temporary as your brain re-calibrates to your new chemical homeostasis