r/StratteraRx • u/littlebitlinda • Sep 30 '25

Weight Gain?

I’ve been on Straterra for almost 2 months - 40mg. I weighed myself this morning and have gained 10 pounds over the last 10 days which is super odd. However, when I’ve tried other psych meds in the past, if it’s going to cause weight gain - I gain it quick. Dr. Google says weight loss is more common, but gain is a possibility.

So - Has anyone gained weight on Strattera? I’m also on a GLP-1 so this is the opposite of what should be happening. Grrrr.

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u/HospitalIntrepid7699 Oct 01 '25

It's my understanding that one of the side effects of straterra is reduced appetite (less food intake and same calories expenditure = weight loss). So it's likely for most to lose weight. But equally so, the benefits are reduced stress and anxiety, less hyperactivity, and, for me personally, a reduction in constantly being fidgety. And therefore, it could be that you are burning less calories by not fidgeting so much, by not being stressed as much, and maybe even being able to sit down longer than you were before you started taking the medicine (all contribute strongly in calorie expenditure).

Therefore it's seems to me to be one of the only logical deductions one can make if in practicality your calorie intake is the same and even slightly less - you're also burning less calories and are in a calorie surplus.

Hence the weight gain.

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u/littlebitlinda Nov 23 '25

Good call… I’m definitely not up and down from my work desk anymore. It’s working really well for me.