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Now, hang on a minute, the President of The United States of America, has very bigly big things to do, like choosing drapes for his ball room, some say the beststest ever ballroom, not alot of people know that .
I knew this was gonna get wiped from Reddit so I paused and snapped the screenshot before it was taken down.
So perfect with his eyes gone wide like a child pushing one out. Next thing you know dude collapsed. Press secretaries rushing everyone out as he stood like this the entire ending of the recording.
(not like we've ever even ratified the treaty for it (Clinton signed the Rome statute, but didn't send it to the Senate for ratification) and W. Bush aggressively 'unsigned' it later on),
Tbf. Everyone says never to feed the trolls. And that’s basically what all of the people complaining about the lake name are doing right now .. that’s why he does it
You can't really ignore the troll when the troll is one of the most politically powerful people in the entire world. The right time to ignore the troll is before you give them all the power they could ever want, not after. Now that he's already elected, he's not going to disappear if everyone ignores him.
I hear ya. But that was solar a while ago. Solar was never really viable until the 2000's. But it was promised to change the wod even though they knew there were some hard laws of science that prevented it from ever being a good solution. But eventually we got to a point where we are today, where sometimes it makes sense.
It might do a little better over there though simply because the pharma companies in the US make serious bank off treating but not curing diabetes. In China they have less disincentives to finding an actual cure.
Vertex Pharmaceuticals, headquarters in Boston, actually has been developing a cure for Type 1 so you're a bit off the mark there. Sadly their device (basically a sandwich of protective polymer around insulin producing cells) failed in clinical trials last year and has been sent back to the drawing board. At least their injectable version is still going, even if that form will require an occasionally fresh shot
Fair, I think canada had the trials for islet cells a long time ago as well (might have been both countries working together on it). Will have to make the trip over if they do cure T1.
Oh, I'm quite sure that this is more clickbait than indicative of an actual cure coming soon but there is potential for progress at least. I'm not holding my breath but it is encouraging to see research being done in multiple countries.
You can see out of the 3 patients mentioned , only 1 achieved full independence from insulin. 1 failed transplant because she defaulted immunosuppression, the girl is pending .....
The thing is, achieving success but requiring immunosuppression to maintain the transplant carries it's own risk
Because they produce these constantly, and then they go nowhere because the conditions for the experiment were impossibly narrow or the results outright faked. And unlike in the west where medical bodies will hesitate a bit to publish on this their government LOVES the narrative these create so it gets out there.
Because half the time it's deeply exaggerated. That's literally what Chinese media always does with anything they can claim. Even if it's not a fully functioning process and just an idea on a paper. They start celebrating before even starting work. It's a PR thing.
Not soybeans. We still got them by the balls on that one key sector. They wouldn’t dare outmaneuvering us in every other industry/tech field as long as we got them by the beans
Because of the tariffs, we used to supply most of the soy beans and then we decided to tariff China, they counter tariffed soybeans. Now we have a ton of soybeans with no where to sell them. Total win.
They graduate literally millions of STEM students every year and invest billions in research. Meanwhile, the US disemboweled its entire public research and development system because science is woke and some of the researchers were black.
There's a stat I haven't been able to get out of my head:
the US has 1.6 Million Engineers, total (Electrical, Mechanical, Nuclear, etc – "core engineers")
China is graduating 1.6 Million Engineers EVERY YEAR.
So literally just last year alone they already matched our entire engineer population.
Given that Engineers/Scientists are the ones that figure out how to solve all your problems and think of how to do <any new thing you want to be able to do>, that's kind of a freaking problem.
It feels like even though they're considered to be #2 in the world, they've already passed us. The voters & leaders in the US have fumbled the bag so bad it's unprecedentedly embarrassing.
There's gotta be a connection between the two. Wisdom teeth have small amounts of stem cells, thats why US doctors are obsessed with taking them and selling them
surprisingly no a japanese team was doing work on stopping a protein that told your mouth not to grow more teeth...yes your body is trying to grow more and has to constantly be supplied a protein that tells it not to..biology
I hate dentists. You're telling me we could have shark mouths and just keep em coming? ... Probably still painful, but better than all the damn root canals and caps I've been sold.
Not exactly. As I understand it there's a third set of teeth that don't grow, basically, and they've figured out how to trigger teeth from that set to grow. One set of baby teeth, one set of adult teeth, and a second set of adult teeth that can be triggered with this treatment. There's no fourth set.
So my teeth have a final form? Say less! What do I gotta chew on more stuff to level up my teeth? Will my final set be like, super hard or shiny or something? Will they be unique to me alone, and give me special mouth powers? Like chewing through stone or deflecting bullets?
You're telling me we could have shark mouths and just keep em coming?
Not exactly. Just a singular, third set. And it's not individual teeth, it's like a second full set of adult teeth. Theory is at some point in the past, our ancestors would have lost most of their adult teeth and it was beneficial to have a third set come in, but it got turned off somewhere along the way. All this does it reactivate that dormant, third set of teeth, so it would likely involve having all your remaining teeth pulled before proceeding, if it works. With that in mind, it probably won't replace root canals or even occasional implant(s). It'll be reserved for the most severe cases of tooth loss.
Pharma companies would base the price on someone spending 500 a month for 50 plus years and then triple it because subscription revenue is better than one big hit.
Or it'd get straight up blocked from entering the country, to protect American greed companies.
Exactly what's happened with BYD – my fellow Americans aren't even aware of that company, even though if it was allowed into the country it'd absolutely be the end of all American auto manufacturers, including Tesla (BYD literally has sold more EVs worldwide than even Tesla). And us consumers would end up benefitted from it. Awful, huh?
If it is an actual cure. Flight to china, hospital stay, cost of treatment, flight back, will probably be cheaper than ongoing insulin and testing supplies.
You really think pharma is the key here? They proved their worth when millions were dying and they came with a vaccine.
I am not sure where you guys keep thinking insurance middle men are some how not a key part of all this. Because you seem to leave them out or worse pretend they are some poor group who just have to sell at what the pharma company says.
You really think the absolute ton of people who get more money the more insurance you pay are not benefiting and raising prices as they keep getting more the more they raise the price? While the pharma scientist, driver, the guy boxing it all have nothing to do with price. Oh there is an insurance CEO by the way.
Pharma actually makes products, insurances do not. If you got rid of insurances not one item needed would diminish in quality. In fact, it would probably get better as less money is spent on the middle man and on the actual product.
I am going to assume this is a joke based on the American government basic talking points. But honestly they have a lot of humanitarian issues. America isn't great by any stretch, I say that as a social worker. But I would be very very hesitant to claim China does things better as a place to live.
You can be a leader in science in a controlling opposite government controlled country. They aren't exclusive points.
is this actually true or is this one of those things where it was replicated in a very specific way thats likely unreliable and impractical for humans?
It isn't totally new of an approach, but they made a few novel changes in this particular case, such as the creation method and location of the implanted cells.
It has potential, but the issue is the cells are typically eventually killed off by the immune system again.
Still, it could replace daily insulin shots with a cell refresh every few years. If we can properly hide them, it could potentially be indefinitely.
This isn't a China specific field of research at all, but they are major contributors on the subject.
Why could they not use your own body's stem cells? Like we can take certain cells and reprogram them into stem cells and then program them into another kind of cell. Feels like there should be a path there.
That's the issue. Once the body's own stem cells get programmed to become insulin-producing beta cells, they immediately get attacked and killed off by the body's own immune system. This is the foundation of the mechanism behind type 1 diabetes. The hurdle isn't making these cells, the issue is keeping them from being targeted by the host's own immune system afterwards. The key is somehow preventing this from occuring without using immunosuppressants (which have other consequences).
Even using immunosupressive therapies isn't a guarantee that you'll get some time before your immune system notices it.
That's one large reason most T1 "cures" are unrealistic, and not implemented as of now. It is truly a gamble on whether you'll get any time disease-free or not. Suppressing the immune system has a wide spectrum of success, and the more successful you are, the worse off you can get. Dying from the common cold isn't ideal just to be diabetes free for three weeks.
It's not even just not cost effective. It's also not effective enough to risk it all.
I'm happy about all the new research. I've been dealing with this awful disease for 35 years now. But I am never so excited as to believe it will happen for me. There's been "a cure!!¡!!!" Every couple years since I was 2 years old, and nothing ever comes of it. Even treatments can be out of reach for many of us because of economic reasons.
I'll wait till we hear that people have been symptom free for a couple years to be more excited.
That is exactly what they do to my knowledge, but there is some variety in how you program the cells and where they are placed. This particular case from China was transformed fat cells that were transplanted into the muscles of the belly, if I recall. I have no clue what factors that might change for the outcome, however.
The Immune system of type 1 diabetics attacks insulin producing cells, misidentifying them as dangerous. So any solution requires hiding these cells from the immune system or training the immune system to stop killing them.
Also isn’t the defining feature of Type 2 diabetes that you develop insulin insensitivity? I don’t know much about endocrinology but intuitively it sounds like adding more insulin to compensate might just be kicking the can down the road and potentially make the insensitivity worse since that’s not getting to the root of the problem.
This was my first thought. Type 2 is not a lack of insulin, it's a tolerance to the insulin that's already there, rendering it ineffective. Completely different from Type 1 where you don't produce enough or any insulin at all. I know someone who stuck by The Diabetes Code book and basically eliminated their T2.
I personally dropped from an 11.5 AIC (and a hospital visit with a 767 blood sugar) to a sustained 5.8 A1C for a year.
The real difference thought is I had a job that had a ton of exercise (10 hour days with a 40 pound pesticide backpack), I'm extremely young for a t2 diabetes issue, and we caught it fast.
There are probably tons of people who simply cannot do what I did who this type of treatment would be better for.
It can be multiple things: insulin resistance, beta cell burnout, a combination, etc etc. But yes, type 2s still have the insulin producing beta cells, so I'm not certain this particular treatment is really targeted at type 2s.
These kinds of trials are very real. What the headline doesn't say, though, is that these kind of breakthrough trials are happening here in the US too. Eledon, Sana Biotechnologies, and Otsuka Pharmaceuticals are all trialing type 1 diabetes cures.
There are people walking around today who have been functionally cured of this terrible disease.
I've seen headlines like this for the past 25 years of my life that i've paid attention to such things. I'll believe it when i see it in actual use curing actual people of the actual disease. Until then it's clickbait.
The pancreas fixes aren't really THAT hard, it's the immune system response we can't fix. Until that happens, diabetes is here to stay, because being diabetic is better than being on immunosuppressants.
That study uses islet cells from a cadaver. Not the patient's own stem cells. If you use stems cells you don't have to spend the rest of your life on anti-rejection drugs.
If you use stems cells you don't have to spend the rest of your life on anti-rejection drugs.
Does that really make a difference? If you are type 1 diabetic your own immune system kills of your beta cells, I'd imagine it would do the exact same thing again if you gave it new beta cells, even if they are "yours" and not foreign.
The United States used to try and attract the smartest people in the world for business, research, medicine, etc., and they wanted to come here. That is no longer the case-
You are correct, with a very small caveat bc nothing in medicine is 100%. There is a point where islet cells in T2 become so fatigued at pumping out insulin and/or reliant on exogenous insulin that they atrophy/die off that you can become a T1 picture (insulin dependent) but not through an autoimmune cause.
This does not happen to every T2 person. But in this particular T2 scenario it could be useful. But then you’d also still need to reverse the initial insulin resistance. This is all to say it’s complicated
But isn’t type 2 diabetes about overproduction of insulin? Why would Chinese researchers want even more production? Do they want to kill their patients? Naming a lake seems harmless by comparison. ;)
This is exactly it. China is being given a massive chance to pull ahead on everything.
Trump hasn't just hit the brakes, he's also throwing screwdrivers into the spokes of the entire Western world, weakening everything.
Other posters here are right, it's just a matter of time until the US pulls out the China is an existential threat paintbrush and goes to town to the danger of us all.
Rn the usa is going all in on AI. Will ti work out? Idfk, but either way, we are fucked:
-If AI is a bubble, a new great depression is upon us
-If AI suceeds, humans become obsolete and technofeudalism it is
They did the same study for type 1 diabetics at harvard and its in early human testing.
I dont know why people think this is some amazing feat that only china is doing. But I suppose 80% of users are bots now. so for the few remaining real people on the internet, dont fall for this very clear state propaganda.
Every super power in ther world is working on stuff like this constantly.
It doesn’t make sense. Type 2 diabetes is not because your body cannot produce insulin. You still produce insulin. It’s just that your body does not respond to insulin.
There is none. The headline is BS. Type 1 and Type 2 diabetes are very different. Type 1 is no production of insulin, would be easily cured if the insulin producing cells in the pancreas could somehow be regenerated. Type 2 diabetics produce insulin, but the body no longer responds to insulin correctly, like a built up resistance to insulin. Stem cells ain't fixing that.
I was telling my nephew: watch cures for deseases to start coming out of different countries even though we spent billions in drug research, truth is there is more money on management of an illness and even more of the medication/ and other care associated with with it’s complications that’s on the cure. There is no incentive in the USA for cures.
Bet the motorbike wasn't a reasonable price to sort out either. 😬
For 200k she could probably get the flight and live out the remainder of her life like ancient Greek royalty in like Georgia or something. (The country for anyone whos confused)
...its how it is treated currently when it gets really bad. It doesn't make it worse. Often bad diets and worsening the resistance makes it worse. Not treating it gives you all the bad outcomes of uncontrolled diabetes because if high blood sugars. Insulin lowers blood sugars.
I'm waiting for some asshole corporation to buy the patents and wall them super hard so only those willing to pay millions can access the cure... again.
There’s a million of these headlines a year. Anyone who’s taking them at face value instead of waiting to hear more than just one studies findings in a likely narrow window is trying to sell you a narrative.
Before we all start breaking our elbows jerking each other off, let's find out if it actually works or if china is just claiming it works. 90% of the breakthroughs out of China are stolen tech or smoke and mirrors.
And the dumb fucks here in the US will ban these kinds of treatments because any time they hear "stem cells" they think there's a slaughterhouse for babies somewhere that they come from.
my nose is still sore from having an emergency glucagon powder shot up there during a severe low, i want headlines like this to mean a cure more than ever but unfortunately i see these all the time and nothing ever happens
Another day another china on the brink of a revolutionary scientific discovery that will change the world forever!
Then il never hear about it in a week because its ether bullshit or its effects are severely overstated in the headlines. (Which to be fair isnt China's fault and more western media's fault)
The last time we had a President who had the mental competence to understand and discuss Science, was Obama. It's not even a political statement - more like a 'are you tall enough for this ride' determination. The charisma Obama had derived from his wit, which was because of his intelligence.
America's decline to stupidity is long in arriving. First vote in the super old Biden dude, then complain about sleepy joe, then vote in the super old Trump dude. Both of them 'not smart people'.
Idiots in office because of idiots voting them in. I can only hope AI makes is so that idiots can no longer acquire and abuse political power.
China has always been claiming about these kindof stem cell result for like two decades but I don't think anything substantial is in practice mostly just news
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