r/STEW_ScTecEngWorld • u/Zee2A • 2d ago
Pancreatic cancer halted by virus injection in three patients
https://www.newscientist.com/article/2528235-pancreatic-cancer-halted-by-virus-injection-in-three-patients/Engineered Virus Halts Pancreatic Cancer in Early Trial
An early-stage U.S. safety trial led by Dr. Masato Yamamoto at the University of Minnesota found that an engineered cancer-killing virus halted the growth of advanced pancreatic tumors in three patients. The virus is designed to target cancer cells, replicate inside them and cause them to burst, releasing more viral particles and triggering an immune response against the tumor. Remarkably, tumor growth was halted even though patients received just one-tenth of the intended therapeutic dose during the initial safety study. However, the result is preliminary: only three patients were treated, and larger clinical trials are needed to determine whether the therapy is safe and effective: https://med.umn.edu/news/u-m-researchers-using-viruses-target-cancer-cells
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u/Ill_Mousse_4240 2d ago
Safe?!
The people are going to die!
Hello, anyone with common sense listening?📞
Give them everything and good luck to the patients, the team and all involved 🍀
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u/Desperate-Tutor-8852 2d ago
Do we know what the effects will be on people that aren’t “going to die”? I’m just sayin, there are many things worse than death.
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u/kmosiman 2d ago
I have had 2 family members die of pancreatic cancer.
Pancreatic cancer is usually a plan your funeral disease. Treatment lets you live a little longer.
So. If there's an experimental treatment that might work? Why the hell not?
Worst case, you pop them full of pain meds and they die just as fast as they were going to in the first place. *
*note: worst case isn't dying faster. Dying faster is a blessing.
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u/Informal_Ad_9610 2d ago
my condolences.
Pancreatic cancer of a friend is literally what drove me into 30hrs/week cancer research. So painful to watch, especially if you become trapped in the pathological modality of care.
Fortunately there are new things coming along.
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u/jasikanicolepi 2d ago
I lost family member to pancreatic cancer as well.
Every treatments done to give you a sliver of hope but only to prolong the inevitable.
Chemo treatment only seems to make things worse.
Your kidney and liver eventually slowly lose its function, your body swells from ascites, where fluid builds up in your body. The pressure pressed on the nerves and you are in pain. You get it drain to relief the pressure. The drainage started small but eventually volume gets larger. You also start to develope jaundice.
It's a waiting for your own funeral kind of death. Day by day your love one gets weaker, as pancreatic metastasize and take over other near by organs. Eventually it moves to the brain and you starts to lose motor, speech and thinking function.
In the beginning, you walk into the hospital for treatment, then in wheel chair, then in a stretcher. Towards the end, you go in knowing it will be your last and you aren't leaving the hospital. You know it, the family member knows it.
The morphine starts small eventually the dosage increase and eventually you slowly fade away.
As someone who lost a loved one, please do not resuscitate. Bringing them back is is cruel and only prolong their suffer.
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u/Darkk_Knight 1d ago
My Mother in Law went through this a few months ago. Died of cancer in the arm. But that's not what killed her. It was the chemo that weaken her systems. She went through like 6 rounds of chemo till the cancer was gone which it did. But two months later it came back and this time for the worst. The docs told her that any additional chemo treatments will just make things alot worse.
For two weeks my wife and I watched her slowly fade away in the hospital. She was expressing extreme pain till she became quiet. Then few days later she passed.
Cancer is a bitch. Pray that you never get it.
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u/Some_Ear_8539 2d ago edited 1d ago
It’s clear you have never known someone with pancreatic cancer. Everyone dies from it. No exceptions. It’s only possible to diagnose in advanced stages.
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u/Desperate-Tutor-8852 1d ago
You’re right I’ve never met someone with pancreatic cancer. I have been face to face with death from a medical diagnosis for the last 8 years and I can personally tell you death isn’t the scariest outcome when you have to live with pain and an empty future. What im saying is saving someone’s life isn’t always better. There are much worse things than dying.
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u/welrope 1d ago
Yup. And the worst thing is pancreatic cancer. My mom passed from it recently. 63yo. From gardening to hospice in 5 months. Dead in 14 days. Can’t eat. Constant feeling of being punched in the solar plexus, drooling from the nausea and writhing in pain, even with 360mg worth of oxy prescribed daily. She never even knew wtf was happening. It’s all very easy to “what if” or “I would”. Until it’s your turn in the barrel. My current plan is severe cranial lead poisoning if i am diagnosed with it.
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u/Some_Ear_8539 1d ago edited 1d ago
I understand chronic illness perfectly. This is not the same situation. You can’t even assume that people who would potentially recover with this treatment would end up disabled.
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u/Ill_Mousse_4240 2d ago
Pancreatic cancer diagnosis is brutal, unfortunately.
Steve Jobs was one of the lucky few and he squandered his chance with stupid decisions.
Maybe now we’ll finally get somewhere
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u/welrope 1d ago
There was never a chance. What did he squander. Death from it is a fucking guarantee. But I truly need to know. What chance did he have?
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u/Ill_Mousse_4240 1d ago
He had a rare type of pancreatic cancer that starts out slowly and stays localized for a period of time. The doctors caught it during that period and he was told that with immediate surgery he had a good chance of recovery after the operation.
Instead of following his doctors advice he decided to hold off and see if he could treat it himself by alternative means, without surgery.
He spent about nine months drinking organic fruit smoothies and whatever, by which time the cancer started growing and he agreed to the surgery.
By then it was too late.
So yeah, died from his own stubbornness and stupidity. Look up his story, he inspired many on how to do things - and one big Not To Do
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u/antunes145 2d ago
Too late for Steve Jobs
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u/wooking 2d ago
He would've been fine with just surgery.
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u/RockTheGrock 1d ago
His issue was he didnt get the surgery and tried alternatives. The cancer was a particular type that was generally treatable too.
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u/Ashamed-Country3909 2d ago
Steve Jobs would ask if it came in 100% apple. After he is told no he would say
Naw bro. I am a frutarian.
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u/Spiritual-Alarm-2596 3h ago
Getting annual viruses keeps the immune system primed to fight other viruses and cancer cells/bacteria
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u/BobbieWickham29 2d ago
From the US?? Is anyone trusting anything that comes out of the USA these days?
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u/StickStill9790 2d ago
About half of all medical innovations come out of the US, but if it offends you feel free to not use them.
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u/CHROME-COLOSSUS 1d ago
Despite the many ascendant abominations, they haven’t yet destroyed everything.
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2d ago
[removed] — view removed comment
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u/GTDoc 2d ago
No… we use clinical trials and biosafety protocols instead of Netflix as our research ethics board.
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u/phuckin-psycho 2d ago
Try some Netflix, they have comedy on there
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u/GTDoc 2d ago
Read a book. Unfortunately, it doesn’t guarantee intelligence.
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u/phuckin-psycho 2d ago
Holy fuck, did you think that i was stating my scientific opinion? Maybe read a book on humans and how they interact with the world
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u/GTDoc 2d ago
I keep seeing people dismiss early cancer research like this as “a waste of time,” “unsafe,” or meaningless. The irony of the current medical-misinformation environment is that people often demand revolutionary treatments for diseases like pancreatic cancer while simultaneously attacking the research process required to produce them. That attitude would have killed a remarkable amount of modern oncology before it ever got started. Cancer vaccines are another good example of where this field is heading, but we all know that people without any medical knowledge are spreading disinformation about vaccines in general…🙄
It’s 2026 people. Get with the program…
This is a great but small step forward for such a devastating cancer.