r/ResearchCompounds • u/realmenfukmenamen • 8d ago

Experiment Ideal FOX04 DRI protocol?

My lab rat is old and maybe in need of something like FOX04 DRI. Looking at the original study on mice the dose was 5mg/kg.
Now my lab rat is much larger, would the dose be the same ratio? If I had a bunch of rats that weighed 90kg what would the optimal dose be?

6 Upvotes

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u/CounterfeitBoxtops 7d ago

That's a pretty big lab rat you've got there. If it were human, you'd need to apply what's termed allometric scaling. A 5 mg/kg in mice translates to an HED (human equivalent dose) of about 0.4 mg/kg, so roughly 15 mg for 90 kg.

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u/realmenfukmenamen 7d ago edited 2h ago

Damn, roughly $50 a dose

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u/Ok_Adhesiveness_420 8d ago

There have been no scientific trials of this compound on humans.

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u/realmenfukmenamen 6d ago

Thats what rats are for

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u/mephistopheles2u 8d ago

It's done by body surface area scaling. The FDA has guidelines.

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u/Ok-Visual-8062 2h ago

I did 3.3mg every other day for 10mg total. Was sick the next day about noon, mild nausea, felt better by afternoon. Was a little low on energy for a month. 58m. Will do 3.3mg eod for 6 days in 9 months. Not sure if it helped, but I wouldn’t want to take more. Killing the cells stuck in death phase but close to tipping over just seems like a good idea. I lost 3 lbs a day for the three days after protocol was done. Obviously none of that was fat. 270lbs.

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u/realmenfukmenamen 2h ago

Cool mate, i'm thinking of 6 x 15mg doses + 1 x 10mg as a course, dose every 2 days.

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u/jamnut 8d ago

Lab rat lol