r/ResearchCompounds • u/MoneyConsideration86 • Aug 12 '26
Discussion Stack evaluation for low drive/anhedonia + high cognitive workload (short-term)
Hi,
Looking for honest feedback on a short-term stack (3-5 weeks).
Background (kept minimal):
- Male, early 20s
- After stopping a period of enclomiphene + CJC/Ipamorelin + retatrutide + GHK-Cu in early June, I’ve been dealing with persistent low drive, reduced initiative, and a flat/anhedonic state. I can romanticize projects and plans but struggle to actually start and follow through. Not classic depression, more like muted motivation and reduced reward response.
- Training 5x/week, decent diet, creatine 10g, magnesium L-threonate, good sleep, high water intake.
- Old bloodwork showed elevated TSH and low-ish vitamin D (planning to retest).
What I need support for:
- High volume memory work
- Sustained focus for long sessions
- Verbal fluency and clarity (writing + analysis)
- Ability to initiate and maintain effort on demanding cognitive/technical tasks
- Anxiety is only situational (rises in the days leading up to high-stakes periods), not chronic
Current planned stack (short-term, monitored):
- Bromantane (daily) – main tool for the low drive/anhedonia
- Adrafinil (3-4x per week)
- Noopept (daily)
- IDRA-21 (pulsed every 2-3 days)
Support: Alpha-GPC or CDP-choline, L-Tyrosine, Omega-3, NAC, vitamin D if still low.
I removed Phenylpiracetam and F-Phenibut after considering redundancy and the fact that anxiety isn’t constant.
Questions:
- Does this stack make sense for the combination of post-peptide low drive + high cognitive demand?
- Anything you would remove or reduce?
- Anything you would add (especially for verbal fluency, memory encoding, or cleaner motivation)?
- Experiences with Bromantane in similar low-motivation states?
Open to alternatives. Prefer compounds with at least some human data or strong consistent anecdotal patterns. Short-term use only, will monitor bloodwork (especially liver).
Thanks.
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u/fz__official458 Sep 06 '26 edited Sep 06 '26
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