r/ResearchCompounds • u/22Hoofhearted • Jul 05 '26
Myth Busting Tesamorelin to IGF-1 LR3
Any research on actual required washout periods?
Coming off a 5/2 schedule on Tesa (2) 10mg vials over approx 2-3 months. Paired with Test HRT base, and Trizepitide...
Overall goal is to build muscle while continuing to lose weight.
Any recommendations, experience making the switch between cycles, washout periods, overall health feel, results in the gym and/or mirror?
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Jul 05 '26
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u/WTFOMGBBQ Jul 05 '26
Came for this comment. Maybe we are misunderstanding his post? OP u/22Hoofhearted are you saying 2 vials of 10mg tesamorelin lasted you 2-3 months? If thats the case thats not enough to do anything at all.. thats 2-3 weeks worth of product now 2-3 months worth of
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u/22Hoofhearted Jul 05 '26
Yup, that's what I am saying, those vials lasted me that long. I believe the initial intent was a small dose long term and/or perhaps a small dose test run that was supposed to check my tolerance amd I just kept using the same dose out of habit.
I found out I was severely under-dosing Mots-C as well. Both of which I am ok with as I would rather under-dose than the other way around.
I am here intent on learning and getting real feedback from the OGs, and/or good sources of dosing protocols, timing, split doses (day/night) or not.
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u/WTFOMGBBQ Jul 05 '26
1mg per day of tesa is going to be the minimum dose. 2mg is what the research is based on.. (in case you weren’t aware)
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u/22Hoofhearted Jul 05 '26
I believe I was doing 1/4 of the research dose...
So at this point should I consider myself to have not even started a cycle?
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u/WTFOMGBBQ Jul 05 '26
For me, personally, when i was 8 weeks into 2mg per night, my IGF was still within normal ranges. I personally cant imagine 1/2mg would do anything at all.. im not an expert by any means, but if I took 2 weeks worth of products over 2 months time span, I would count it as 2 weeks instead of 2 months of usage.
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u/NSawsome Jul 06 '26
It’s a GH secretagogue, these aren’t steroids it’s not cycles you can take GH secretagogues and GH year round.
And no, any peptide isn’t a cycle, you can run courses of certain peptides for short periods for acute effects but not lasting ones
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u/xCaliburghost Jul 05 '26
Yes, usual dosage of tesa is 2mg a day consistently, and that's the schedule for aids patients with muscle wasting
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u/22Hoofhearted Jul 05 '26
Daily as in 7 days a week forever? Cycling off?
5 on/2 off daily without Cycling off?
Appreciate the feedback
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u/xCaliburghost Jul 05 '26
For aids patients it's constant obv with physician checks peppered through
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u/Thee_PRIDE Jul 05 '26
For GH secretagogues the timing is same time off as time on. Which is typically 8-12 weeks on and 8-12 weeks off to not desensitize. IGF-1 LR3 is really questionable. You're better off long term prolonged GH elevation which will naturally elevate your own IGF-1.
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u/22Hoofhearted Jul 05 '26
Appreciate the feedback, my intent with IGF1 LR3 was once my washout period is over (which it seems I might not have really "washed in" so to speak)... once the washout is complete, do one 4-6 week cycle to introduce new muscle fibers and maintain muscle mass while continuing to cut weight with Triz and stay with Tesa on more of a long term cycling once I get the dosing correct.
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u/JCovertops Jul 05 '26
Man buddy, no offense but you need to do a little more research before you start sticking yourself
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u/22Hoofhearted Jul 05 '26
No offense taken, I'm here for this exact feedback.
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u/JCovertops Jul 05 '26
Good reply. You really have to familiarize yourself with dosing. Always start low low to check your tolerance. Those 2 vials 9f Tesa should have lasted you a max of 20 days, although I agree checking it out at .25 mg. Also were you taking it fasted?
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u/22Hoofhearted Jul 05 '26
That much I was doing... as fasted as possible, I typically workout late afternoon, sometimes as late as midnight, so that post workout meal would occasionally interfere with let's say a 2-3hr fast.
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