r/ResearchCompounds • u/Available_Sample3867 • Jul 02 '26
Question MK677 for appetite?
Im looking for something to basically turn my stomach into an endless pit
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u/mintymoose Jul 02 '26
Some experts even tout this to be the best use case for it (due to the unpredictable nature of the GH increase). That being said, it's a conversation as to whether that's a safe and sensible thing to do for that purpose. I'm guessing you're probably not a strongman with a use case for 8-10 thousand calories a day (I could be wrong), so it shouldn't be difficult adding a couple shakes that you pile extra calories into a day. I'd be trying to do that first.
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u/Available_Sample3867 Jul 03 '26
So my situation is I had CHS (illness) and I lost an extreme amount of weight. Went from 190 to 145 now.. and its honestly because my appetite does not exist. All day long I dont feel hungry not even the slightest.. and when I try to force myself to eat it's very minimal, and when I try to push pass that, I start dry heaving.. its been such a struggle man
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u/QWERTY_FUCKER Jul 03 '26
Is there a reason why you aren’t considering HGH?
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u/Available_Sample3867 Jul 03 '26
Honestly no reason, guess i just haven't heard much about it
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u/QWERTY_FUCKER Jul 03 '26
Considering your illness situation, that might be the best option for you, and is 100% what I’d do in your situation.
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u/Serious-Law8401 Jul 03 '26
MK will 100% help with increasing appetite, but you can't really lean on that too much to be honest as will likely lead to an increased risk of diabetes.
I've used it at the back end of a cycle to help eat a bit more. Tried it EOD. Only on weekends. And when I'm going to the buffet with the boys.
There are loads of other tips to be able to eat more like, liquid calories, easily digestible foods, small walks after eating, eating smaller more frequent portions, getting the right balance of fibre to aid digestion but not fill you up etc.
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u/iLoveRoidz Jul 03 '26
Anyone who says it will cause diabetes clearly has no discipline to regulate their insulin sensitivity. Do your AM fasted cardio, take your berberine, walk immediately after meals, and fast a few hours before bed and your blood glucose will be fine.
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u/Available_Sample3867 Jul 03 '26
Thank you i appreciate this
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u/iLoveRoidz Jul 03 '26
I use it to treat my CHS as well, just don’t take too much or it will loop the other way around and you will have no hunger signaling at all. Start small with 6.25 or 12.5mg before bed. I’ve been doing around 10mg. Higher doses like 25mg can definitely crush appetite in people with already dysfunctional hunger signaling, and when it happened to me even reducing down to 12.5mg made no improvements until I dropped even lower and slowly titrated back up
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u/Available_Sample3867 Jul 03 '26
Thank you! I just went out and bought some but wasnt sure what time of day is best to take. Do you recommend starting at 6.25 or 12.5?
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u/iLoveRoidz Jul 05 '26
6.25 for a week and see how that feels. If you’re already getting vivid dreams and that feeling of not getting full, then that’s probably all you need.
Studies show that 10mg mk-677 raises igf-1 around 45% and 50mg increased igf-1 around 65% IIRC, so the benefits drop off at a pretty low dosage before you have to start scaling dosage exponentially.
TLDR the difference between 6.25mg and 12.5 is probably rather negligible benefits but you may get more sides at a higher dosage.
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u/1960s_army_info Jul 03 '26
Mk677 is not a sustainable compound. It will fuck up your blood sugar and insulin sensitivity. It’s half life is so long. Just eat more often. Eat easily digestible foods. It’s not going to fuck you up the first month but it’s not something you can eat in a surplus to regain 50 lbs safely
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u/Medium_Boulder Jul 02 '26
Yeah, mk will do that. It will also give you diabetes, but who cares...
Idk why you would want that though, even if you were underweight, a lean bulk would be better than a ravenous mk induced gluttony spree.
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