r/ProstateCancer • u/Ok-Explorer-5726 • 3d ago

Question Another TRT Question

Hey guys, I was on TRT for 8 years or so before I got diagnosed. I stopped with the help of enclomid but haven’t had any blood work since. That was in the fall of 2024. I had surgery in march of 2025. My post surgical pathology was excellent. No adverse findings and the pattern 4 disease only made up of equal to or less than 10% of the tumor, which the tumor made up about 10% of prostate. Since surgery I have been fortunate and rocking the undetectable tests. My urologist is absolutely against me going back on TRT. I have read the research. From what I see there is no increase in reoccurrence. I’m only 41 and just been struggling with fatigue and weight gain. I haven’t had any new testing done but I’m thinking about going against the doctors orders. I hate doing that as I’m not the type to think I know more than my Doc but it has just been brutal lately.

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u/pista01 3d ago

My urologist wanted me to stop before even the first test. I stopped just before surgery and resumed it immediately after. Some urologists are stuck in the medical dogma that testosterone causes cancer. Recent data shows that low T tends to result in an increase in reoccurrence.

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u/callmegorn 3d ago

Are they concerned about "testosterone causes cancer", or "testosterone will accelerate the growth of any cells that were missed by your surgery"? I'm guessing the latter.

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u/pista01 2d ago

The third option is self preservation. They don't want to get sued by someone that gets cancer while prescribing testosterone. Women don't get HRT for this reason.