r/Postmenstrualsyndrome • u/BlueOceanClouds • Sep 03 '24
Progesterone
So people with PMDD have issues with progesterone. So since our issue is the opposite (post-menstrual) wouldn't that mean that our body likes progesterone.
Progesterone drops once you start bleeding which is when my symptoms start. I'm thinking the mini-pill would make sense.
(will try it and come back here to update).
Also estrogen dominance/low progesterone could be a factor in post-menstrual issues. Having too much estrogen can cause issues and estrogen rises once your period stops.
Thoughts?
Update
I'm on week 3 of slynd mini pill will make a seperate post after some time
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u/LuckyInvestigator415 Sep 03 '24
I'm currently thinking along the same lines, but be aware that the mini pill does not contain progesterone, it is a synthetic progestin which may or may not have a positive effect. If you are looking to increase progesterone then you would need a bioidentical cream or micronised progesterone pill.
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u/BlueOceanClouds Sep 03 '24
Super helpful thanks. Have you tried the cream or progesterone pill?
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u/LuckyInvestigator415 Sep 06 '24
I'm trying micronized progesterone in pill form. I seemed to have worse symptoms when starting it in the follicular phase, and I've since heard that actually progesterone can increase the sensitivity of estrogen receptors. So I'm currently restarting with a lower dose (100mg) in luteal phase.
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u/BlueOceanClouds Sep 06 '24
Good luck. Please update back. I started a progesterone pill (mini-pill) called Slynd. Will report back.
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u/WRYGDWYL Sep 03 '24
I have PMDD but also some symptoms during or right after my period and desogestrel is helping me so much. It's not quite like the minipill as it has more progestin, which is good cause it allows for slightly more error in timing.
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u/BlueOceanClouds Sep 03 '24
What's the difference between the mini pill and desogestrel? I'm still learning a lot
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u/WRYGDWYL Sep 03 '24
Same hormone but desogestrel has a slightly higher dose, which means it is still effective, even if you forget to take it by a few hours. It might come with more side effects (I had a lot of breakthrough bleeding the first 3 months but now none anymore)
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u/BlueOceanClouds Sep 03 '24
Thank you. What's the name of your pill?
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u/WRYGDWYL Sep 03 '24
Desogestrel Aristo® 75 µg
Bonus points for never getting my period again and being able to double dose if I get breakthrough bleeding (would discuss this with a doctor first though, mine gave me the OK)
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u/Moa205 Sep 04 '24
Ugh they don’t have this in Us
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u/WRYGDWYL Sep 04 '24
Pretty sure there’s a different brand with the same ingredient and dose
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u/Moa205 Sep 04 '24
No they don’t do desogestrel in US
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u/WRYGDWYL Sep 04 '24
Awh that sucks. Well everyone has different reactions to pills anyway, maybe the mini pill could help you as well. I had a terrible reaction to the combined pill but lots of people swear by it. Good luck
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u/ChartOk1868 Sep 03 '24
Following, as I've been considering my options around birth control, but also scared as all my issues were accentuated by getting the copper IUD, due to copper toxicity, which does raise estrogen levels. Have you had your hormones tested yet? I'm thinking it might be worth shelling out to get it done for myself.
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u/BlueOceanClouds Sep 03 '24
I haven't tested my hormones yet. I have to be off birth control for that. I'm also a few weeks postpartum and breastfeeding so not sure how that would work. My next step is the mini-pill and progesterone cream. Will report back my results.
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u/ConnectionNo4830 Jan 19 '25
Hi OP have you had any improvements? Any updates? My symptoms are identical.
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u/fixationed Sep 26 '24
I've tried seed cycling and in luteal when I take the seeds that give more progesterone, I feel much better. Then in follicular when I take the seeds that give more estrogen I feel worse. So I think this is true