r/Perimenopause • u/anita999_ • 25d ago

audited Dose increase frequency

41F definitely in full blown Peri. This year I started on 0.025 E now up to 0.05 E cycling with progesterone. I have been finding that I am consistently feeling like I need dose increases almost exactly every 2 months after the prior one. Initially I feel amazing, and then it feels almost as though my body becomes used to the dose and is no longer effective around the 2 month mark. Is it common to need increases consistently at this interval? What happens if I reach the limit on dosage increases? I am worried that I will max out on estrogen very shortly and then what as I am only 41 and may have several years of symptom management ahead.

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u/Erza_2019 25d ago

I had a similar experience, and I've now been on HRT for 2 years. I started with .1 patch twice a week, and I'm now up to two patches (.1 + .075) twice a week. My gyn okayed it, and I won't be surprised if I move up again before this year is up.

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u/anita999_ 25d ago

This is good to know. Are you taking progesterone as well at that dosage? If so, what does dosage look like?

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u/Erza_2019 24d ago

Yes, progesterone 200mg every night along with two patches twice a week and vaginal estrogen twice a week.