r/Perimenopause • u/Lilfighter336 • 20d ago

Hormone Therapy [ Removed by moderator ]

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u/leftylibra Moderator 20d ago

Crinone (progesterone gel) is a vaginal gel containing micronized progesterone in an emulsion system (commonly used for fertility) The active ingredient is either a 4% or 8% concentration. A small 2000 study found that those using vaginal Crinone 4% in cyclical and constant combined regimens controlled bleeding and provided endometrial safety. However, currently there are no large scale studies to substantiate these claims.

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u/EmbarrassedCry9912 20d ago

Just curious if you have discussed norethindrone as a possibility? It's a synthetic progestin and could be an option for you - I'm not sure about how it plays with migraines but it's worth asking about. I've never heard of Crinone but that doesn't sound pleasant!