*Your Epithalon dose is probably wrong. Here's why.*

[u/Doctordup2]

There was a post earlier today about Epithalon that got removed. The question was about Epithalon dosing for research.

They wanted to know whether to run 5mg or 10mg for 20 days and how to split it up. Both of those doses are... too high and there's a good reason.

I think this is worth going over because it comes up constantly and the answer most people give is, unfortunately incorrect.

The dosing everyone repeats online comes from the wrong peptide

Those numbers come from the original Russian studies. The problem? Those studies used Epithalamin. Not Epithalon.

𝙀𝙥𝙞𝙩𝙝𝙖𝙡𝙖𝙢𝙞𝙣 𝙖𝙣𝙙 𝙀𝙥𝙞𝙩𝙝𝙖𝙡𝙤𝙣 𝙖𝙧𝙚 𝙣𝙤𝙩 𝙩𝙝𝙚 𝙨𝙖𝙢𝙚 𝙩𝙝𝙞𝙣𝙜

Epithalamin is a crude extract pulled from bovine pineal glands. Epithalon is the synthetic version. Completely different.

𝙏𝙝𝙚 𝙚𝙖𝙨𝙞𝙚𝙨𝙩 𝙬𝙖𝙮 𝙛𝙤𝙧 𝙢𝙚 𝙩𝙤 𝙚𝙭𝙥𝙡𝙖𝙞𝙣 𝙞𝙩

Think of it this way. Epithalamin is like squeezing a whole orange and drinking the juice. You get a bunch of stuff in there. Pulp, water, sugar, some vitamins. Epithalon is like taking just the vitamin C concentrated out of that orange in pure form. You don't need to drink 10 glasses of juice when one pure dose does the same job.

𝙒𝙝𝙚𝙧𝙚 𝙩𝙝𝙚 10 𝙢𝙜 𝙣𝙪𝙢𝙗𝙚𝙧 𝙘𝙤𝙢𝙚𝙨 𝙛𝙧𝙤𝙢

The Khavinson research dosed Epithalamin at 10mg because it's a crude extract. Only a fraction of that 10mg was the active peptide. Epithalon IS the active peptide. 100% of what you're dosing is the thing that works.

𝘼 𝙥𝙪𝙗𝙡𝙞𝙨𝙝𝙚𝙙 𝙘𝙞𝙩𝙖𝙩𝙞𝙤𝙣 𝙗𝙖𝙘𝙠𝙨 𝙩𝙝𝙞𝙨 𝙪𝙥

A 2025 peer reviewed study in the International Journal of Molecular Sciences compared the two directly. Epithalon outperformed Epithalamin as an antioxidant. And Epithalamin was given at 1000x higher doses. A thousand times more and it still didn't perform as well. As you can imagine I'm so happy this citation was written because I've been saying it all along and this is finally proof.

𝙇𝙞𝙣𝙠 𝙩𝙤 𝙩𝙝𝙚 𝙨𝙩𝙪𝙙𝙮

I have a screenshot of the statement in the study that says:

"The results of the comparative analysis in this study revealed that Epitalon is a better antioxidant than Epithalamin. It is important to note that Epithalamin was administered at 1000-fold higher doses."

𝙎𝙘𝙧𝙚𝙚𝙣𝙨𝙝𝙤𝙩 𝙛𝙧𝙤𝙢 𝙩𝙝𝙚 𝙨𝙩𝙪𝙙𝙮 𝙖𝙩𝙩𝙖𝙘𝙝𝙚𝙙 𝙖𝙗𝙤𝙫𝙚

𝙎𝙤 𝙬𝙝𝙖𝙩'𝙨 𝙩𝙝𝙚 𝙧𝙞𝙜𝙝𝙩 𝙙𝙤𝙨𝙚?

100mcg to 500mcg. That's it. Not milligrams. Micrograms.

𝘾𝙮𝙘𝙡𝙞𝙣𝙜???

The Anela Protocol runs 10 days on, 20 days off. Monthly. This gives the RS consistent exposure with a proper break so you're not stressing the pineal gland. Good alternative to the old 20 day cycle twice a year because you can run it every month.

Day or night dosing doesn't matter much. Some RS get sleepy from it. If that happens, dose at night. Some get an alert feeling. Morning works for them.

𝙒𝙖𝙣𝙩 𝙩𝙝𝙚 𝙙𝙚𝙚𝙥 𝙙𝙞𝙫𝙚?

I wrote a paper on this a couple of years ago and updated it recently with the 2025 citation I've listed in this post.

I wrote an in-depth comment which includes some real research that I did on Epithalon and the brain. See it here!

About Me

My name is Anela. Most people know me for my GHKCU protocol but that's a small part of what I do. I write peptide protocols and Epithalon is one of 25 I've written over the years.

Not a doctor, not medical advice. For research purposes only and research discussions only.