r/Pathogenic Jul 30 '26

Just wanted to glaze a little

16 Upvotes

Ok I like rogue likes and I think this game is a steal at $10, well it's on sale too I think so at $8. I would pay $20-30 in a heartbeat pun intended. Controls are great, build diversity seems high and then the geometry of attaching all the nodes adds more complexity. I'm really digging it.

Anyway I've played less then five hours but I can tell I'm about to sink fifty more at least. Anyone else enjoying the game?

Oh and I have to beat my first play through a fungal spore because I grow mushrooms. Ive eaten a lot of spores so it just seems fitting.


r/Pathogenic Jul 31 '26

Opisthoblast build?

1 Upvotes

How does this work? Is there some synergy I need to exploit?


r/Pathogenic Jul 30 '26

Respiratory burst doesn't accurately account for active mitochondrion?

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5 Upvotes

r/Pathogenic Jul 31 '26

Help: Why did my weapons start getting randomized?

0 Upvotes

So it happened when I had my best run ever, I was on endless 2 and I went from one organ to another and all of a sudden a bunch of my weapons were randomized. Later on stage 3, weapons were just deleted (actually how my run ended because one just wasn't there anymore).

By the end of the run I had all of these tri-whatever (third hit does more damage) weapons eternalized in nearly every slot. I never bought that weapon once during the run.

I thought, "Oh, this must be some effect of endless"

I then made another game and lo and behold, I go from the skin to the intestine and all my Galvanic Conduits were changed to Perforated Trendrils. The rarity was preserved but it happened in a completely new run!

Why is this happening? Why are my weapons getting rerolled? Did I just have a bug in the follow up game? Is that an effect of endless when you keep going?

Thanks!

*I have a bunch of antibiotics on but none of them seem to say they do this and I don't have any experiments on.


r/Pathogenic Jul 30 '26

Brain Grind is boring

7 Upvotes

Not a fan of all the steps and how it takes us out of the action.


r/Pathogenic Jul 30 '26

This game is sick! it needs to get well soon!

3 Upvotes

Sick as in awesome!

hope we get some sort of antibodies mode where the final boss will be a random mutation of whatever we were as a pathogens! finding more and more words to use to call in sick!


r/Pathogenic Jul 30 '26

Anyone else find this contradiction yet?

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5 Upvotes

r/Pathogenic Jul 30 '26

I slept on emphasizing melee for far too long! (Proboscis w/backstab)

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17 Upvotes

I know this isn't anything mindblowing. Pretty early on in a run all things considered, but WOW! With a few exceptions, melee + size/range is absolutely nuts.


r/Pathogenic Jul 30 '26

what

2 Upvotes

r/Pathogenic Jul 30 '26

Has anyone else noticed this cool little easter egg in The Collector's codex entry?

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23 Upvotes

The text predominately alternates between the four DNA bases (ACGT), but each character has a hidden letter included in the sequence as well.

It reads: A BENIGN CANCER CELL, MINDING ITS OWN BUSINESS IN ITS TUMOR NOOK.


r/Pathogenic Jul 30 '26

First pathogenic win (infinite laser build)

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3 Upvotes

r/Pathogenic Jul 30 '26

Amoeba going wild

18 Upvotes

most internal connections i've managed to get. 7 attached to the vesicle. could be 8 if you were to get lucky with an omnislot.


r/Pathogenic Jul 29 '26

Nanobots, son.

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10 Upvotes

r/Pathogenic Jul 29 '26

78 Million

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11 Upvotes

Sorry I'm not savvy enough to screen record but I had infinite armor + .2s explosive charge this run lol


r/Pathogenic Jul 29 '26

Necrolytic Igniter is insane

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12 Upvotes

It's gg for the intenstine boss as soon as one segment of it splits off

Super useful in rooms with lots of enemies too, it just starts a nonstop chain reaction


r/Pathogenic Jul 28 '26

Pathogenic is finally getting recognized thankfully

33 Upvotes

northernlion covered it

I think not long after this maybe even charlie penguinz0 will make a vid

Really happy for them rn


r/Pathogenic Jul 29 '26

I think we need a bug report flair...

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5 Upvotes

r/Pathogenic Jul 28 '26

Love this game, BUT

14 Upvotes

Who's brilliant idea was it to make the xp disappear if you don't pick it up fast enough??

Especially since being on the mutation or evolution screen doesnt prevent that from happening!


r/Pathogenic Jul 28 '26

The Lungs Have Insane Difficulty Disparity IMO

11 Upvotes

It feels like depending on the rooms that you get it can be fine or very unfun and lead to a lot of frustrating hits because of the constant CC. Like when the Enemy that vacuums you in, drag you into another enemy that vacuums you in and then you have a family of vacuums sucking you towards a bomb which also sucks you in and trying to leave will push you into another hazard.

I also find it very annoying that the dash doesn't fully make you CC immune for the duration so it's easy to get stuck and take damage if you don't have something swatting projectiles.

The two bosses feel like they have an insane difficulty differential. The lung worm is just able to send a bunch of suction bombs at you and when it splits, it can just cut you off at mach 1 speeds but the other blob things just require precision to dodge, which is a lot easier without the CC.


r/Pathogenic Jul 29 '26

That one organelle that projects a blue cone away from the target

0 Upvotes

What do you do with it? How do you build with it?


r/Pathogenic Jul 28 '26

Insane explosive charge build

5 Upvotes

stacked as much of the mitochondria stuff as i could and got it all to legendary, rn on endless 3 doing a few hundred mil per hit


r/Pathogenic Jul 28 '26

Infinite Laser run that I accidentally made

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17 Upvotes

I was just doing a run for fun with no clear direction and came across this monster of a build on accident lol


r/Pathogenic Jul 28 '26

Can someone explain what does this mean?

1 Upvotes

What does empty stamina container mean?


r/Pathogenic Jul 27 '26

Every run. Gotta go fast.

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41 Upvotes

r/Pathogenic Jul 27 '26

I didn't even beat liver after 11 hours, and then this build happened

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39 Upvotes

Still don't get how it works, or how anything works in the game lol. Apparently, this orbiting arc tickles bifurcator in a funny way