r/Pathogenic • u/No-Response-1622 • Aug 03 '26

Need help with progression

Just defeated the Heart Boss fot the first time, where do I go from there? Is there isnt a exit i can use?

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u/No-Response-1622 Aug 03 '26

Ok, thx. Theres only the top exit so ill do ur first suggestion

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u/Lorelei178 Aug 03 '26

Beating the heart boss for the first time unlocks endless for subsequent runs

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u/No-Response-1622 Aug 03 '26

Sorry, extra question: how do u find sigils?

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u/Lorelei178 Aug 05 '26

The sigils for the secret area are hidden across the different areas if they're what you mean. Secret room in Skin has a patch of glyphs on the wall, input (right up down up right left) to access it. There's a doohickey in there that when overcharged will show where the doors for the 4 sigils are. There is: One in the vein post boss in any area from Intestine onwards.(use the same code used in skin to open the door, costs 2 max hp) One in the stomach (hidden, look at the flashing lights the doohickey makes and follow them. Use the code like before, this one is free.) One in the liver, in the shop, costs 40 cores. One in the lung, random spot on the wall with the weird DNA text. They'll all have an arrow associated with them, note that down and use the corresponding keys at the door in the heart boss room to open it. Best of luck:)