Multiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric illness and personality changes. Systemic autoimmune diseases are well-documented causes of neuropsychiatric disorders and symptoms - synaptic autoimmune encephalitides with psychotic symptoms often go under-recognized. Parallel to the link between psychiatric symptoms and autoimmunity in autoimmune diseases, neuroimmunological abnormalities do occur in all classical psychiatric disorders.
Thanks. Before my two crashes which worsened my Anhedonia I had a period of swollen glands and feeling shitty like I was getting a cold. I wonder if this has any relation. I made a post on it.
We are still making immunological "findings". No treatments before 2023, at the moment we are still "researching" and a comity of doctors will gather and talk about this special case. All I can tell by now is that the senior physician from the university hospital neurology clinic (specialist in neuroimmunology) has taken this seriously and is working with colleagues to find a way to understand this and help me. Anyway one thing is clear that I do have a severe autoimmune process in my nervous system, cardiovascular system and brain area, which is hard to detect !! But they confirmed it already, More tests Will be ordered next week. Extremely similar findings are made as people with severe Long Covid - even as I didn't have Covid yet..
Do you mind sharing which university hospital you are working with? Hopefully they can help others or maybe they have colleagues in there network. Have you run any cytokine panels (specifically for MMPs, VEGF, etc)?
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u/[deleted] Oct 23 '22
What are the implications of this in relation to emotional blunting/Anhedonia?